Comparison of chronic groin pain in patients with or without mesh fixation with tacks undergoing Total Extra Peritoneal hernia repair for unilateral inguinal hernia : a randomized control trial - Nil

Start Date25 Nov 2024

Sponsor / Collaborator

Lady Hardinge Medical College

CTRI/2024/10/075615

/ Not yet recruitingNot ApplicableIIT

A randomised controlled trial to compare the use of fan retractor and Nathanson retractor for operative view score after liver retraction in laparoscopic bariatric surgery. - NIL

Start Date30 Oct 2024

Sponsor / Collaborator

Lady Hardinge Medical College

100 Clinical Results associated with Lady Hardinge Medical College

0 Patents (Medical) associated with Lady Hardinge Medical College

4,189

Literatures (Medical) associated with Lady Hardinge Medical College

01 May 2025·Pediatric Neurology

Electroencephalography in Preterm Infants for Predicting Neurodevelopmental Outcomes: A Systematic Review and Diagnostic Test Accuracy Meta-Analysis

Review

Author: Trevisanuto, Daniele ; Bandyopadhyay, Tapas ; Bandiya, Prathik ; Kumar Krishnegowda, Vijay ; Ramaswamy, Viraraghavan Vadakkencherry ; Balasubramanian, Haribalakrishna

BACKGROUNDElectroencephalography (EEG) and amplitude-integrated EEG (aEEG) have been utilized to predict neurodevelopmental impairment (NDI) in preterm infants.METHODSMEDLINE, SCOPUS, Embase, Web of Science, and Cochrane Library were searched from inception until November 1, 2023. Observational studies evaluating EEG and aEEG and neurodevelopment assessment performed at least after six months corrected age (CA) were included. A diagnostic test accuracy (DTA) meta-analysis using a Bayesian random-effects bivariate model was performed. QUADAS-2 was used to assess the risk of bias, and GRADE approach was used to ascertain the certainty of evidence.RESULTSThirty-eight studies (n = 4667) were included in the systematic review of which 26 studies (n = 3363) were synthesized in a DTA meta-analysis. EEG and aEEG had a sensitivity of 63.9% (95% credible intervals [CrI]: 52.1%, 76.3%) and specificity of 87.6% (80.9%, 94.1%) for the outcome of any NDI (<1 S.D. from the mean value for the CA). For the outcome of severe NDI (<2 S.D.s from the mean value for the CA) (10 studies, n = 1075), the sensitivity was 59.7% (42.3%, 75.9%) and specificity was 85.2% (72.7%, 92.4%). Evidence certainty was very low to low. Subgroup analysis of studies that had utilized Bayley Scales of Infant and Toddler Development between 18 and 30 months CA (12 studies, n = 1202) for neurodevelopmental assessment revealed a sensitivity of 59% (42.3%, 74.7%) and specificity of 83.7% (75.8%, 90.1%) for any NDI.CONCLUSIONEEG and aEEG possibly have suboptimal sensitivity and an acceptable-to-high specificity in predicting any NDI and severe NDI in preterm infants.

28 Apr 2025·Indian Journal of Clinical Anaesthesia

Effect of patient’s position on the success rate of subarachnoid block in parturient undergoing caesarean section: A prospective cohort study

Author: Gupta, Anshu ; Kohli, Pramod ; Tabing, Mary

01 Apr 2025·BMJ Open Quality

Quality improvement initiative to improve safe injection practices by nurses in labour room of a tertiary care centre, India

Article

Author: Gauba, Anu ; Pradeep, Jeena ; Kumari, Prabha ; Puri, Manju ; Pradeep, Charuta

Safe injection practices (SIP) are a set of measures intended to prevent transmission of infectious disease between one patient and another, and between a patient and healthcare provider during the preparation and administration of injectable medications. Unsafe injection practices put both the patient and healthcare personnel at risk of infection.SIP involves administration of rational injection by a qualified and well-trained person using a sterile device (syringe, needle, etc), adopting sterile technique and discarding the used devices in a puncture-proof, specially designed container for appropriate disposal. Any breach in the process makes the injections unsafe and hazardous to patients and healthcare workers (HCWs).To implement SIP, the quality improvement team in the labour room initiated an improvement process with the aim of increasing the percentage of compliance with SIP from the existing 20%–80% within 6 weeks from 6 February to 21 March 2024. The team followed Point of Care Quality Improvement methodology to improve the compliance with SIP.The team developed a 15-point practice observation checklist aligned with WHO and Center for Disease Control (CDC) guidelines. This checklist outlined the steps involved in SIP and used to directly observe the process of preparing and administering injections for adherence to SIP. Each item was scored ‘1’ if performed correctly and ‘0’ if not in the checklist. The compliance was calculated in percentage for data analysis and plotted on a time series chart.The team tested a total of 12 plan-do-study-act to achieve the desired aim (80%). The median compliance rate rose to 87% in the first half of the sustenance phase, which came down to 67% in the later part highlighting the challenges in demand–supply chain of resources and attitude shift among HCWs in maintaining SIP. The lessons learnt are generalisable and can be replicated in similar settings.

100 Deals associated with Lady Hardinge Medical College

100 Translational Medicine associated with Lady Hardinge Medical College

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