
| Disease Domain | Count |
|---|---|
| Hemic and Lymphatic Diseases | 1 |
| Immune System Diseases | 1 |
| Endocrinology and Metabolic Disease | 1 |
| Top 5 Drug Type | Count |
|---|---|
| Small molecule drug | 1 |
| Diagnostic radiopharmaceuticals | 1 |
Target |
Mechanism HIF-PHs inhibitors |
Originator Org. |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. China |
First Approval Date17 Dec 2018 |
Mechanism Mitochondrial complex I (NADH dehydrogenase) modulators [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePreclinical |
First Approval Ctry. / Loc.- |
First Approval Date- |
Start Date01 Jan 2028 |
Sponsor / Collaborator Region Stockholm [+1] |
Start Date15 Jun 2026 |
Sponsor / Collaborator Region Stockholm [+1] |
Start Date01 Jun 2026 |
Sponsor / Collaborator Karolinska Institutet [+15] |

| Drug(Targets) | Indications | Global Highest Phase |
|---|---|---|
Roxadustat ( HIF-PHs ) | Diabetic Nephropathies More | Phase 2 |
[18F]BCPP-BF ( Mitochondrial complex I (NADH dehydrogenase) ) | Chronic Kidney Diseases More | Preclinical |
18F-AZD9272 ( mGluR5 ) | Central Nervous System Diseases More | Pending |





