Jiamusi

To address challenges in heat dissipation and electromagnetic compatibility in miniaturized electronic devices, this study reports the construction of a Ni-NiO heterostructure on fluorinated boron nitride (FBN).Ni-MOF was uniformly coated onto FBN via a solvothermal synthesis process, followed by high-temperature annealing to obtain FBN@Ni-NiO composites.The FBN@Ni-NiO-700 composite achieved exceptional performance, with a min. reflection loss (RL_min) of -67.64 dB at 2.87 mm thickness in the X-band and a maximum effective absorption bandwidth (EAB_max) of 5.78 GHz.The Ni-NiO heterostructure synergistically enhances electromagnetic wave dissipation through magnetic and antiferromagnetic interactions and optimizes impedance matching, yielding broad absorption bandwidth.Also, with its innovative structural design and exceptional electromagnetic loss properties, the FBN@Ni-NiO composite demonstrates remarkable performance advantages, achieving an outstanding maximum RCS reduction of 19.82 dB m².In TC, FBN@Ni-NiO-700/UV-cured resin composites achieved a 537 % increase, from 0.2500 W m^-1 K^-1 to 1.5915 W m^-1 K^-1 at 30 wt% filler content.This pronounced enhancement is ascribed to the formation of continuous and well-ordered thermal conduction pathways facilitated by the synergistic interplay between FBN and the Ni-NiO heterostructure, which significantly improves phonon transport efficiency.Addnl., the Ni-NiO interface effectively reduces phonon scattering between the thermal fillers and the polymer matrix.These results underscore the promising potential of FBN@Ni-NiO composites for applications in 5G communication systems, radar technol., and aerospace engineering.

Research has indicated that aberrant amygdala connectivity is a crucial neurobiological underpinning of juvenile depression. This study aimed to further identify resting-state dynamic functional connectivity (dFC) changes between the lateral amygdala (LA), medial amygdala (MeA), and whole-brain voxels, as well as their correlations with clinical symptoms in adolescents with depression.

The bilateral LA and MeA were selected as regions of interest, and the sliding window method was applied to investigate dFC changes in 47 adolescents with depression, compared with 35 sex-, age-, and education-matched healthy controls (HCs). Subsequently, the relationship between the dFC variability values and Patient Health Questionnaire-9 and Simplified Coping Styles Questionnaire (SCSQ) scores in the patient group was investigated.

Compared with HCs, there was reduced dFC variability between both the left LA and left MeA and right precentral gyrus; both the right LA and right MeA and left median cingulate and paracingulate gyri; and the right MeA and right cuneus in adolescents with depression. Furthermore, the dFC variability between the right MeA and right cuneus correlated positively with negative coping scores of the SCSQ (r = 0.414, p = 0.005) in adolescents with depression.

These findings confirm abnormal dynamic functional pathways of amygdala subregions in adolescent depression, and suggest that abnormal dFC may be involved in the neural mechanisms underlying the pathogenesis of adolescent depression.

Human cytomegalovirus (HCMV), a prevalent double-stranded DNA enveloped virus, poses a threat to immunocompromised individuals. The current clinical detection methods are insufficient in sensitivity, highlighting the need for more effective approaches.

We designed and screened RPA primers and crRNA based on the UL123 gene of HCMV. Evaluate the HCMV-RPA-CRISPR detection method using cloned plasmids and the whole-genome samples of HCMV-infected cells. Conduct RPA-CRISPR/Cas12a reactions with 48 clinical samples and compare the results with those of PCR-Fluorescent Probe Method in clinical applications and the qPCR method for detecting the UL123 gene.

The optimized RPA-CRISPR system exhibited high sensitivity and specificity for HCMV detection. The positive rate of clinical sample detection was approximately 20.5 % (6/48) higher than that of the clinical detection method.

Currently, the sensitivity and early detection of HCMV in clinical settings are still limited. The UL123 gene of HCMV is characterized by high transcription in the early stage and high conservation. The RPA-CRISPR/Cas12a technology exhibits high sensitivity in detecting the HCMV UL123 gene, and it is expected to provide a more effective method for the early specific detection of HCMV infection.