Delving into the Latest Updates on Imam Muhammad Bin Saud Islamic University with Synapse

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Digestive System Disorders

Neoplasms

Small molecule drug

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Neoplasms	1

Top 5 Drug Type	Count

Small molecule drug	1

Top 5 Target	Count

MAP3K21(mitogen-activated protein kinase kinase kinase 21)	1

BACKGROUNDImposter Syndrome (IS), or Imposter Phenomenon (IP), is marked by persistent self-doubt and fear of being exposed as a fraud despite success. It's prevalent in high-achieving fields like medicine and is linked to anxiety and perfectionism. The Clance Imposter Phenomenon Scale (CIPS) is the most common assessment tool. This study aims to translate and validate an Arabic version of CIPS for Arabic-speaking populations.METHODSThis cross-sectional study was conducted at King Saud University, Riyadh, from August to September 2024, using a convenient sampling method. The survey gathered demographic details and included the Arabic version of the CIPS, the General Self-Esteem Scale (GSES), and The Big Three Perfectionism Scale (BTPS). Data were analyzed using IBM SPSS 22 (p < 0.05). Construct validity was assessed through Exploratory and Confirmatory Factor Analysis. Internal consistency (Cronbach's alpha ≥0.7), test-retest reliability (ICC >0.75), and discriminant validity were evaluated. Concurrent validity was examined using structural equation modelling and Pearson's correlation with GSES and BTPS.RESULTSA total of 477 participants (66.5 % female, mean age 21.1 ± 2.0 years) completed the questionnaire. The Arabic CIPS demonstrated a three-factor structure in exploratory factor analysis (KMO = 0.936, Bartlett's test p < 0.001), with confirmatory factor analysis supporting good model fit (CFI = 0.87, RMSEA = 0.07). Internal consistency was excellent (Cronbach's α = 0.90), and test-retest reliability was acceptable (ICC = 0.71). Discriminant validity was supported by significant score differences across quartiles. CIPS correlated negatively with general self-efficacy (r = -0.39, p = 0.001) and positively with self-critical perfectionism (r = 0.68, p = 0.001) and rigid perfectionism (r = 0.46, p = 0.001), confirming its construct validity.CONCLUSIONThe Arabic CIPS is valid and reliable for use among medical and non-medical populations.

01 Mar 2025·Ear, Nose & Throat Journal

Capillary Hemangioma Involving the External Auditory Canal: Case Report and Review of the Literature

Review

Author: Alshalan, Afrah ; Binhazzaa, Amal

Hemangioma is a frequently observed soft tissue tumor that can be classified into cavernous, capillary, and venous subtypes. It occurs frequently in the head and neck; however, with rare reports of hemangiomas in the external auditory canal (EAC). The present study describes the case of a 57-year-old male patient who presented to our center with a subsequent diagnosis of capillary hemangioma of the EAC. The entire lesion was surgically removed, with no evidence of recurrence on the subsequent follow-up.

01 Mar 2025·International Journal of Pediatrics and Adolescent Medicine

Knowledge, attitudes, and practices of Saudi parents regarding antibiotic use for children: A cross-sectional study

Author: Aldakail, Mohammad ; Shuiel, Hadeel Khalid Bin ; AlMubayedh, Alaa Ahmed ; Almubayedh, Tasneem ; Alqahtani, Alwaleed ; Alkhamis, Ibtisam Hussain

Background: Raising awareness about the proper use of antibiotics is crucial, as misuse can lead to significant side effects and antibiotic resistance, similar to challenges faced in chemotherapy treatments.Methods: This cross-sectional study assessed the knowledge, attitudes, and practices of Saudi parents regarding antibiotic use for children, involving 356 participants recruited from pediatric clinics across Saudi Arabia.Results: The findings revealed notable misconceptions, such as the belief that antibiotics are effective against viral infections and the premature cessation of prescribed courses. While 75.35% of parents recognized that unnecessary antibiotic use contributes to resistance and 88.5% understood the importance of completing courses, 27.13% admitted they might stop antibiotics early if symptoms improved. Demographic data indicated that most participants were women (78.9%), aged 31–40 years (36.2%), with college-level education (83.0%), and employed (72.1%), including 28.1% in healthcare. Despite 61.9% having health insurance and 77.5% rarely using antibiotics without prescriptions, no significant relationship was observed between education or income and attitudes toward antibiotic misuse (P > 0.05).Conclusion: These findings highlight persistent misconceptions and risky practices, emphasizing the need for targeted educational interventions and policy measures to enhance understanding and adherence to proper antibiotic use and to combat antibiotic resistance effectively.

100 Deals associated with Imam Muhammad Bin Saud Islamic University

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100 Translational Medicine associated with Imam Muhammad Bin Saud Islamic University

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Pipeline

Pipeline Snapshot as of 13 Jul 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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