A review. Rotavirus is the most important cause of acute infectious enteritis, it is stable even in the environment and its infectivity is very strong, and 3-5 hygiene is improved, it is said that they will be infected with rotavirus at least once. Rotavirus vaccine is effective for the control of oral rotavirus enteritis, based on evidence of efficacy, safety and epidemiol. studies in each country, vaccine guides drastically reduce the prevalence of fetal rotavirus avian enteritis. In this paper, the Rotarix, from among rotavirus vaccines was discussed, and introduce the target and mechanism of vaccines, development history, verification of efficacy, and epidemiol. vaccine impact and safety.