|
MechanismCLDN18.2 inhibitors |
|
|
|
Inactive Indication- |
Drug Highest PhasePhase 1/2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
|
Mechanismtissue factor inhibitors |
|
|
|
Inactive Indication- |
Drug Highest PhasePhase 1/2 |
First Approval Ctry. / Loc.- |
First Approval Date- |
一项评估XNW28012治疗晚期实体瘤患者的安全性、耐受性、药代动力学和初步抗肿瘤活性的开放性、多中心I/II期临床研究
[Translation] An open-label, multicenter Phase I/II clinical study evaluating the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of XNW28012 in patients with advanced solid tumors
评估XNW28012在晚期恶性实体瘤受试者中的安全性与耐受性。
[Translation] To evaluate the safety and tolerability of XNW28012 in subjects with advanced malignant solid tumors.
XNW27011在局部晚期或转移性实体瘤患者中的首次人体Ⅰ/Ⅱ期研究
[Translation] A first-in-human phase I/II study of XNW27011 in patients with locally advanced or metastatic solid tumors
I期(剂量递增阶段)
确定XNW27011的最大耐受剂量(MTD)和/或Ⅱ期推荐剂量(RP2D)。
Ⅱ期(剂量扩展阶段)
评估XNW27011在RP2D剂量下的客观缓解率(ORR)。客观缓解率包括完全缓解(CR)和部分缓解(PR)。
[Translation] Phase I (dose escalation phase)
Determine the maximum tolerated dose (MTD) and/or recommended dose (RP2D) of XNW27011.
Phase II (dose expansion phase)
Evaluate the objective response rate (ORR) of XNW27011 at the RP2D dose. The objective response rate includes complete response (CR) and partial response (PR).
100 Clinical Results associated with Shanghai Sinovent Biopharmaceutical Co., Ltd
0 Patents (Medical) associated with Shanghai Sinovent Biopharmaceutical Co., Ltd
100 Deals associated with Shanghai Sinovent Biopharmaceutical Co., Ltd
100 Translational Medicine associated with Shanghai Sinovent Biopharmaceutical Co., Ltd