Guangdong Zhongda Tianyi Biological Technology Development Co., Ltd.

Primary study objective: To evaluate the safety of naringin tablets after multiple administration in healthy Chinese subjects. Secondary study objective: To evaluate the pharmacokinetic characteristics of naringin and its metabolite naringenin after multiple administration in healthy Chinese subjects. Exploratory study objective: To study the intestinal flora metabolism of naringin tablets after multiple administration in healthy Chinese subjects.

1. To evaluate the safety and tolerability of naringin tablets after single-dose escalation in healthy Chinese subjects. 2. To evaluate the pharmacokinetic characteristics of naringin and its metabolite naringenin after single-dose escalation in healthy Chinese subjects. 3. To evaluate the effect of food on the pharmacokinetic characteristics of naringin and its metabolite naringenin after oral administration of naringin tablets on an empty stomach or after a standard test meal in healthy Chinese subjects.