The aim of our study is to measure the level of awareness, preconceptions, and level of fear regarding epidural analgesia among childbearing women in KKUH in Riyadh.

Start Date01 Aug 2022

Sponsor / Collaborator

King Khalid University Hospital

[+1]

NCT04716439

/ Unknown statusNot ApplicableIIT

Effect of Total Intravenous Anesthesia (TIVA) With Magnesium Sulfate on Intra-Operative Neuromonitoring (IONM) in Patients Undergoing Spine Surgery

Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression. This randomized placebo-controlled, double-blind study was designed to evaluate the effect of magnesium sulfate on the total anesthetic and analgesic consumption using the clinical parameters in addition to the effect on IONM reading.

Start Date01 Feb 2021

Sponsor / Collaborator

King Khalid University Hospital

NCT04680923

/ CompletedNot ApplicableIIT

Efficacy of Combined Periportal and Preperitoneal Local Anesthetic Infiltration (CPPLAI) in Laparoscopic Sleeve Gastrectomy Patients

The high demand for bariatric surgery due to the increasing prevalence of obesity worldwide necessitate evidence-based clinical pathway such as Enhanced Recovery After Bariatric Surgery (ERABS). The paradigm of surgery has been shifted from open to laparoscopic in morbidly obese patients. Laparoscopic Sleeve Gastrectomy (LSG) is the most common procedure performed in our institute for sustained weight loss and amelioration of obesity-related comorbidities. Pain control in ERABS is one of the key factors for improved outcomes. Surgery induced acute postoperative pain, stress response and fatigue lead to prolonged convalescence and hospital stay. Optimal titrated safe postoperative pain management in LSG patients still remains a challenge.

Start Date08 Dec 2020

Sponsor / Collaborator

King Khalid University Hospital

100 Clinical Results associated with King Khalid University Hospital

0 Patents (Medical) associated with King Khalid University Hospital

1,982

Literatures (Medical) associated with King Khalid University Hospital

01 Dec 2025·Lung

Comparative Efficacy of CFTR Modulators: A Network Meta-analysis

Article

Author: Rao, Saad T ; Iftikhar, Imran Hasan ; BaHammam, Ahmed S ; Nadama, Rufai ; Janahi, Ibrahim

PURPOSEThe objective was to study comparative efficacies of cystic fibrosis transmembrane conductance regulator (CFTR) modulators, vanzacaftor-tezacaftor-deutivacaftor (VTD), elexacaftor-tezacaftor-ivacaftor (ETI), tezacaftor-ivacaftor (Tez-Iva), and lumacaftor-ivacaftor (Lum-Iva) in people with cystic fibrosis (pwCF), aged ≥ 12 years, carrying at least one F508del-CFTR-allele.METHODSData from randomized controlled or randomized active comparator trials were included in this network meta-analysis which used frequentist approach for comparing the efficacy of drugs and ranking based on P-scores. Outcomes of interest were mean differences in percentage-predicted forced expiratory volume in one second (ppFEV₁), CF questionnaire-revised respiratory domain (CFQ-R) scores, sweat chloride (SwCl) levels, and odds ratios (OR) for serious adverse events (SAE).RESULTSData from 13 studies were analyzed. Compared to placebo, the effects of VTD and ETI on ppFEV1 were almost quadruple of Tez-Iva and Lum-Iva (VTD: 12.78 [95% confidence intervals: 6.41; 19.15] and ETI: 11.95 [7.40; 16.50]) and almost seven times of Tez-Iva and Lum-Iva for CFQ-R (VTD: 21.23 [- 28.72; 71.18] and ETI: 19.27 [10.56; 27.98]). A statistically significant difference was noted between VTD and ETI in SwCl reduction (mean difference: - 8.59 [- 15.53; - 1.65]). There were no statistically significant ORs for SAEs for any CFTR modulators but VTD, ETI, and Tez-Iva were least associated with SAEs (ORs were 0.15 [0.01; 1.79], 0.49 [0.31; 0.78], and 0.74 [0.50; 1.09], respectively, as compared to placebo). Overall, P-score ranking ranked VTD as first and ETI as second, followed by others.CONCLUSIONVTD and ETI were more efficacious than Tez-Iva and Lum-Iva in pwCF with at least one F508del-CFTR-allele.

01 May 2025·Current Problems in Cardiology

Future of magnetic sensors applications in early prediction of cardiac health status

Review

Author: Khan, Muhammad Shah Zeb ; Sahli, Majed ; Makki, Layal Khaled ; Alfifi, Somayah Mohammad ; Alwanian, Wanian M ; Alharbi, Hajed Obaid ; Jackson, Matthew ; Khan, Shahid Ullah ; Al-Nafjan, Abdulmajeed Abdullah ; Alrumaihi, Faris

The evolution of health monitoring technologies has highlighted the need for accurate and reliable sensors, particularly in the context of cardiac health. This review examines the potential of magnetic sensors as a superior alternative to optical sensors for the early prediction of cardiac health status. Optical sensors face significant challenges, especially for individuals with darker skin tones, where increased light absorption adversely affects measurement accuracy. Additionally, issues such as sensor-skin coupling and motion artifacts further compromise the performance of optical devices. In contrast, magnetic sensors offer a compelling solution by providing consistent readings irrespective of skin tone, thereby enhancing inclusivity in health monitoring. These sensors leverage magnetic fields, which do not rely on light penetration, allowing for improved coupling with the skin's surface and maintaining accuracy during motion. This paper discusses recent advancements in magnetic sensor technology and their implications for cardiac health applications, emphasizing the potential for increased accuracy and reliability in predicting cardiac outcomes. As healthcare shifts toward more personalized and precise monitoring solutions, magnetic sensors emerge as a promising frontier, addressing critical challenges in current health status prediction methods. By focusing on these innovative technologies, we aim to contribute to the ongoing discourse on enhancing cardiac health monitoring and fostering more equitable healthcare solutions.

25 Mar 2025·Cureus

What Clinicians Should Tell Patients About Wearable Devices and Data Privacy: A Narrative Review

Review

Author: Pergolizzi, Joseph V ; Varrassi, Giustino ; LeQuang, Jo Ann K ; El-Tallawy, Salah N

The recent growth of wearable medical device technology in fitness trackers, smartwatches, smartphone apps, and patient monitoring systems has created people-generated health data (PGHD) that may benefit medical science with large amounts of continuous real-world data. The prevalence of these devices speaks to their broad popularity and user-friendliness and may lead us one day to a more fully "connected healthcare system." Meanwhile, data security, confidentiality, and privacy issues have emerged in these hackable systems. Despite the promise of anonymized data, data can sometimes be re-identified. However, even without that step, data breaches may reveal information (name, address, date of birth, social security number, and so on) sufficient for identity theft. Clinicians are often asked about the utility and value of wearable devices or monitors. Still, most are unaware that data from these systems may be transmitted, stored, and even sold without the user's specific knowledge. Despite the confidentiality of medical information, cybersecurity surrounding wearables and monitors remains relatively lax, making them comparatively easy targets for cyber villains. It is also important that efforts be made to make PGHD more secure since medical data may be of great value to telehealth applications and AI-physician assistants. Clinicians should actively inform patients about the risks and benefits of wearables and similar devices.

100 Deals associated with King Khalid University Hospital

100 Translational Medicine associated with King Khalid University Hospital

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