Zhejiang Zhongtong Pharmaceutical Co., Ltd

Main study objectives: To study the pharmacokinetics of the test preparation ciprofloxacin hydrochloride tablets (specification: 500mg, licensee: Zhejiang Zhongtong Pharmaceutical Co., Ltd.) and the reference preparation ciprofloxacin hydrochloride tablets (trade name: Ciprobay®, specification: 500mg, licensee: Bayer) in healthy adult subjects after a single oral administration in the fasting and fed state, and to evaluate the bioequivalence of the two preparations. Secondary study objectives: To evaluate the safety of the test preparation (T) ciprofloxacin hydrochloride tablets and the reference preparation (R) ciprofloxacin hydrochloride tablets (Ciprobay®) in healthy subjects after a single oral administration in the fasting and fed state.

Main study objectives: To study the pharmacokinetics of the test preparation azithromycin dry suspension (specification: 100 mg, produced and licensed by Zhejiang Zhongtong Pharmaceutical Co., Ltd.) and the reference preparation azithromycin dry suspension (Zithromax®, specification: 100 mg, produced and licensed by Pfizer Pharmaceuticals Co., Ltd.) in healthy adult subjects after single oral administration in fasting and fed state, and to evaluate the bioequivalence of the two preparations in fasting and fed state. Secondary study objectives: To study the safety of the test preparation azithromycin dry suspension and the reference preparation azithromycin dry suspension (Zithromax®) in healthy adult subjects after single oral administration in fasting and fed state.