Delving into the Latest Updates on Fujian Institute of Research on The Structure of Matter with Synapse

Overview

Currently, the zinc anode faces significant challenges such as dendrite growth, corrosion, and hydrogen evolution, which severely limit the practical applications of aqueous zinc-ion batteries. To address these issues, this study designed a zinc anode (denoted as CG@Zn) coated with a gel composed of carboxymethyl cellulose sodium (CMC) and glucose. This coating featured dual functionalities: it regulated the directional transport of Zn²⁺ ions and constrained the electrochemical activity of interfacial water molecules, effectively inhibiting the growth of zinc dendrites and significantly reducing the occurrence of corrosion and hydrogen evolution side reactions. Benefiting from these advantages, CG@Zn exhibited excellent electrochemical performance. Under testing conditions of 5 mA cm^-2/1 mAh cm^-2, the symmetric battery assembled with CG@Zn demonstrated over 1000 h of stable cycling, achieving a cycle life five times that of bare zinc electrodes. Furthermore, the full cell configuration of CG@Zn//NaV₃O₈·1.5H₂O with a matching zinc sulfate electrolyte maintained a capacity retention of 67.1 % after 15,000 cycles at 10 A g^-1, significantly outperforming the rapid capacity decay observed in bare zinc batteries under the same conditions. Therefore, this study successfully developed an effective bifunctional gel coating for zinc anodes using CMC and glucose, paving the way for the development of safe and eco-friendly aqueous zinc-ion batteries.

01 Aug 2025·Journal of Colloid and Interface Science

Tumor-microenvironment-activated bimetallic oxide nanoplatform for second near-infrared region fluorescence-guided colon tumor surgery and multimodal synergistic therapy

Article

Author: He, Liangzhen ; Ying, Yunfei ; Dang, Yongying ; Zhang, Ziqian ; Xu, Chao ; Wang, Peiyuan ; Liu, Xiaolong ; Li, Siyaqi ; Xue, Fangqin

Colon cancer, characterized by its high incidence and mortality rates, continues to present a significant challenge in cancer treatment. To address this, we present a novel ZnCe based nanocarrier featuring stacked mesopores and rough surface, indocyanine Green (ICG) is encapsulated within these mesopores (ZnCe&ICG). This innovative nanoplatform demonstrates effective accumulation in tumor regions and can be triggered to generate efficacious reactive oxygen species (ROS) in the weakly acidic and high H₂O₂ conditions typical of tumor microenvironments. Enhanced fluorescent imaging using improved tumor-to-background ratio has proven effective in precisely delineating tumor margins from surrounding healthy tissue. With the guidance of this second near-infrared region (NIR II, 1000-1700 nm) fluorescence imaging technique, tumors are completely excised, resulting in negligible instances of in situ recurrence or metastasis observed 30 days following surgery. Notably, under 808 nm laser irradiation, the nanoplatform exhibits a high photothermal conversion efficiency, leading to localized heating that further amplifies ROS production via multi ion synergetic catalysis for tumor cell killing. These results underscore the potential of tumor microenvironment-responsive ZnCe-based nanocomposite as a fluorescence imaging contrast agent and chemodynamic agent for cancer treatment, particularly when combined with NIR light activation.

01 Aug 2025·Journal of Colloid and Interface Science

Low-voltage flexible organic transistors utilizing passivated polyelectrolyte dielectrics for tactile sensing and braille recognition

Article

Author: Ma, Yunlong ; Wang, Xiaoyan ; Liu, Changdong ; Liu, Yuting ; Zheng, Qingdong ; Yin, Zhigang

Organic field-effect transistors (OFETs) utilizing polyelectrolyte dielectrics offer low-power operation and good signal amplification, making them well suited to pressure sensor applications. However, pristine polyelectrolyte dielectrics suffer from high leakage currents and instability under device operation. Here, we develop novel passivated polyelectrolyte dielectrics to enhance electrical performance of low-voltage flexible OFETs, achieving the reduced hysteresis and the significantly improved mobility from 0.04 to 1.17 cm² V^-1 s^-1. The optimized OFETs with passivated polyelectrolyte dielectrics are integrated as flexible pressure sensors, affording high sensitivity (297.2 kPa^-1) at -2 V, wide response range (0-70.1 kPa), and fast response in milliseconds. Inspired by human skin, the OFET pressure sensor successfully simulates biological synaptic behaviors, including excitatory postsynaptic currents, paired-pulse facilitation, and the transition from short-term memory to long-term memory, which are crucial for processing complex signals. Furthermore, intelligent touch recognition of braille characters with an accuracy of ∼98% is achieved by designing the low-voltage OFET pressure sensor array and combining it with algorithms. These results provide new insights into advanced dielectrics and low-power OFET sensors for potential applications in skin-like artificial synapses, and human-machine interaction systems.

100 Deals associated with Fujian Institute of Research on The Structure of Matter

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Pipeline

Pipeline Snapshot as of 09 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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