In this study,a new national anti-allergic drug,rupatifen fumarate,was developed and a new crystalline form of rupatifen fumarate(crystal A) was preparedThe target compound was synthesized by acid addition salt method,and the crystal type A was characterized by powder X-ray diffraction,differential scanning calorimetry(DSC),scanning electron microscope and other phys. methods.The characterization results showed that the crystal type A was a rod-shaped crystal,the characteristic peak of crystal A was(2θ±0.2)° at 13.6°(23%),21.2°(30%),29.1°(40%).Its m.p. was(154±2) °C and decomposition occurs at about(180±2)°C.Through the study,the compound and crystal A of rupatifen fumarate were of great reference significance for the development of proprietary drugs of rupatifen fumarate.♂