Chengdu Nuohe Shengtai Biotechnology Co., Ltd.

Main study purpose: To observe the similarity of pharmacokinetic/pharmacodynamic characteristics of single intramuscular injection of test preparation salmon calcitonin injection [Specification: 1mL: 50IU, provided by Chengdu Novo Shengtai Biotechnology Co., Ltd.] and reference preparation salmon calcitonin injection (trade name: Miacalci®, specification: 1mL: 50IU, licensee Future Health Pharma GmbH) in adult healthy menopausal women. Secondary study purpose: To observe the safety of test preparation and reference preparation in adult healthy menopausal women.

Primary objective To observe the pharmacokinetic characteristics of a single oral dose of 0.6 mg (fasting and after meals) of the test preparation desmopressin tablets (specification: 0.178 mg based on C46H64N14O12S2, produced by Jiangsu Yongan Pharmaceutical Co., Ltd.) and the reference preparation desmopressin acetate tablets (trade name: Minirin, specification: 0.2 mg/tablet, produced by Ferring International Center SA) in healthy adult Chinese subjects, and to preliminarily evaluate the bioequivalence of the two preparations when taken orally in fasting and after meals. Secondary objective To observe the safety of a single oral dose of 0.6 mg (fasting and after meals) of the test preparation and the reference preparation in healthy adult Chinese subjects.

Primary objective: To preliminarily evaluate the tolerability and safety of healthy adult volunteers after a single intravenous injection of different doses of STC007 injection. Secondary objective: To evaluate the pharmacokinetic (PK) characteristics of a single intravenous injection of different doses of STC007 injection in healthy adult volunteers.