Mengke Medical Technology (Shanghai) Co Ltd

To evaluate the safety, tolerability, and pharmacokinetic characteristics of intravenous and oral MRX-4 in healthy Chinese subjects.

To evaluate the pharmacokinetic characteristics and safety of MRX-I tablets 800 mg after multiple oral doses in healthy subjects.

The pharmacokinetic characteristics of MRX-I tablets in subjects with moderate liver impairment were studied and compared with those in healthy subjects with normal liver function, so as to provide a basis for the formulation of dosing regimen for MRX-I tablets in patients with liver impairment.