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Immune System Diseases

Hemic and Lymphatic Diseases

Neoplasms

Small molecule drug

CAR-T

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Hemic and Lymphatic Diseases	1
Infectious Diseases	1
Immune System Diseases	1
Neoplasms	1

Top 5 Drug Type	Count

CAR-T	1
Small molecule drug	1

Top 5 Target	Count

BCMA(B-cell maturation protein)	1

Industrialization and globalization have increased the demand for petroleum products that has increased a load on natural energy resources. The escalating fossil fuel utilization has resulted in surpassing the Earth's capacity to absorb greenhouse gases, necessitating the exploration of sustainable bioenergy alternatives to mitigate emissions. Biofuels, derived from algae, offer promising solutions to alleviate fossil fuel dependency. Algae, often regarded as third-generation biofuels, present numerous advantages owing to their high biomass production rates. While algae have been utilized for their bioactive compounds, their capability as biomass for the production of biofuel has gained traction among researchers. Various biofuels such as bio-hydrogen, bio-methane, bio-ethanol, bio-oil, and bio-butanol can be derived from algae through diverse processes like fermentation, photolysis, pyrolysis, and transesterification. Despite the enormous commercial potential of algae-derived biofuels, challenges such as high cultivation costs persist. However, leveraging the utilization of algae byproducts could improve economic viability of biofuel production. Moreover, algae derived biofuels offer environmental sustainability, cost-effectiveness, and waste reduction benefits, promising novel opportunities for a more sustainable energy future. Moreover, advancements in the field could lead to patents that drive innovation and commercialization in algae-based biofuel technologies.

01 Dec 2025·Molecular Biology Reports

LncRNA-miRNA-mRNA regulatory axes as potential biomarkers in cervical cancer: a comprehensive overview

Review

Author: Patel, Dimple ; Thankachan, Sanu ; Kabekkodu, Shama Prasada ; Sreeram, Saraswathy ; Kavitha, K P ; Suresh, Padmanaban S

Despite the recent advances in vaccination and treatment strategies, cervical cancer continues to claim numerous lives every year. Owing to the fact that non-coding RNAs (ncRNAs) such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) interact with coding transcripts, and effectuate key roles in the tumorigenesis and metastasis of cervical cancer, there has been extensive research in recent years to explore their potential as biomarkers for early detection, or as therapeutic targets. Through this review, we aim to provide a comprehensive overview of the recent advancements in discoveries about cervical cancer-associated lncRNA-miRNA-mRNA axes, their dysregulation, and their roles in various signaling pathways associated with the growth, survival, invasion, and metastasis of cervical cancer cells. We further discuss the potential therapeutic strategies to utilize the dysregulated lncRNAs as diagnostic and prognostic biomarkers, and as therapeutic targets to ameliorate the prognosis of cervical cancer.

01 Jun 2025·Journal of Fluids Engineering

The Influence of Vortex Flow in the Dispersed Phase on Droplet Formation Dynamics

Author: Dutta, Sushanta ; Maurya, Tara Chand Kumar

AbstractThis work explores the characteristics of a two-phase system's dispersed phase flow that interacts inside the microfluidic channel at the junction. Direct visualization and μ-particle image velocimetry measurements are performed on the interaction of two immiscible fluids in different stepped flow-focusing (SFF) channels for droplet formation. The capillary instabilities produce the counter-rotating vortex flow in dispersed phase fluid at the interface, which plays a significant role in droplet formation. The vortex flow has been analyzed using various data processing techniques. The effect of flowrate and step channel dimensions on the evolution of the vortices generated during droplet thread propagation is studied. The strength of the vortex and momentum flux led to the development of more bulging shapes in the droplet thread. Also, this study exhibits transient flow characteristics during the detachment stage and contributes to understanding its influences on mass transfer at the microlevel dimensions.

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Pipeline

Pipeline Snapshot as of 23 Jan 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

2

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

BCMA-Directed CAR-T(ImmunoACT) ( BCMA )	Multiple Myeloma More	Preclinical
SG-B-52	MRSA - Methicillin resistant Staphylococcus aureus infection More	Preclinical