Delving into the Latest Updates on University of Azad Jammu and Kashmir with Synapse

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Nervous System Diseases

Small molecule drug

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A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Nervous System Diseases	3

Top 5 Drug Type	Count

Small molecule drug	3

Top 5 Target	Count

MAO-A x MAO-B	2
NF-κB(Nuclear factor NF-kappa-B complex)	1

Laterite is a geol. formation in tropical and subtropical regions with high iron and aluminum content.It is extensively used in cement production, water filtration, and the formation of geopolymers.The optical emission spectrum of laterite confirmed the presence of Ca, Al, Si, Mg, Fe, K, Li, Ti, Cu, Sr, Na, Ni, Mn, Rb, Ba, O, H, and N.CF-LIBS was employed to determine the relative elemental concentrationThe quant. results encounter a significant challenge due to self-absorption, resulting in a nonlinear relationship between the emission signal and concentrationThe escape factor method, which numerically determines the fraction of radiation escaping the plasma without reabsorption, is an effective approach for correcting self-absorption.The escape factor, determined by optical thickness and spectral line shape, was incorporated in the equation of spectral line intensity to correct for self-absorption.This correction in emission intensities ensures a strong linear and reliable correlation with concentrationBoltzmann and Saha-Boltzmann plots were constructed to estimate the plasma temperatureThe determined relative elemental concentration using one-line CF-LIBS was compared with the results obtained by inductively coupled plasma mass spectrometry (ICP-MS).The comparative study of relative elemental concentrations illustrates significant improvement in CF-LIBS using the escape factor.

01 Jul 2025·Physica B: Condensed Matter

Enhanced UV photodetection with Au-doped WO3 thin films: Responsivity, detectivity, and self-powered characteristics

Author: Sarfraz, Areeba ; Farhanulhakim, Mohd ; Saeed Khan, Raja Azhar ; Masood, Asad ; Waheed, Anjam ; Ahmed, Rizwan ; Khan, Taj Muhammad ; Ahmed, Nasar

Tungsten oxide (WO₃), with its exceptional optical, elec., and structural properties, is a highly promising n-type semiconductor.In this study, boron-doped p-Si substrates were used to fabricate Au-doped WO₃ thin films via pulsed laser deposition, employing a Q-switched Nd:YAG laser (266 nm wavelength, ∼10 mJ pulse energy) at a substrate temperature of 600 °C and 10 Pa pressure.Comprehensive characterization was conducted using XPS, XRD, FE-SEM, EDX, Raman spectroscopy, FTIR, and four-probe measurements.The resulting p-Si/n-WO₃ heterojunction device demonstrated an excellent UV photodetection performance, achieving a responsivity of ∼80 A/W, specific detectivity of 7.07 x 10¹¹ Jones, and fast response times of 130 ms (rise) and 180 ms (fall).Under reverse-bias conditions, the device exhibited significant UV photo-response at room temperatureNotably, the Au-doped WO₃ thin films showcased self-powered photodetector behavior, producing a short-circuit current (Isc) of ∼0.06 μA and an open-circuit voltage (V_oc) of ∼0.48 V without an external power source.These findings highlight the superior performance of p-Si/n-WO₃ heterojunctions for UV photodetection, demonstrating high responsivity, detectivity, and self-powered capabilities.This study positions Au-doped WO₃ thin films as a promising material for advanced optoelectronic applications.

03 Jun 2025·Numerical Heat Transfer, Part B: Fundamentals

Nanoparticles hybridization in bidirectional flowing of Prandtl–Eyring material with temperature-dependent conductivity: A numerical approach

Author: Ahmad, Iftikhar ; Faisal, Muhammad ; Riaz, Muhammad Bilal ; Zan-Ul-Abadin, Qazi

100 Deals associated with University of Azad Jammu and Kashmir

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100 Translational Medicine associated with University of Azad Jammu and Kashmir

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Pipeline

Pipeline Snapshot as of 18 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Preclinical

3

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Compounds 5f(UAJ&K) ( MAO-A x MAO-B )	Alzheimer Disease More	Preclinical
Compounds 5a(UAJ&K) ( MAO-A x MAO-B )	Alzheimer Disease More	Preclinical
Jietacin Derivative(Kitasato University) ( NF-κB )	Alzheimer Disease More	Preclinical