Beijing Mange Pharmaceutical Technology Co., Ltd.

According to the relevant provisions of bioequivalence tests, the reference preparation was selected as Ezetimibe Atorvastatin Calcium Tablets (trade name: Atozet®, specification: 10mg/10mg) produced by Organon Healthcare GmbH, and the test preparation Ezetimibe Atorvastatin Calcium Tablets (specification: 10mg/10mg) produced by Jilin Deshang Pharmaceutical Co., Ltd. and provided by Beijing Mange Pharmaceutical Technology Co., Ltd. was used for fasting and postprandial human bioequivalence preliminary test to evaluate the pharmacokinetic characteristics of the two preparations and provide a reference for the formal test design. At the same time, the safety of healthy subjects after oral administration of the test preparation and the reference preparation was observed.