There is a huge load of chronic kidney disease (CKD) patients in India who are at risk of premature morbidity and mortality coupled with inadequate public health infrastructure. Adult patients of CKD admitted in our institute and who gave written informed consent were included in the study. Mean age of subjects in our study was 46.16 ± 15.03 years with 63% of them in 31-60 yr age bracket and with male predominance (66%). The etiol. factors of CKD were hypertension (66%), diabetes mellitus (22%), glomerulonephritis (14%), obstructive uropathy (11%), and autosomal dominant polycystic kidney disease (5%), with some patients having multiple factors. The common factors associated with hospital admission were severe anemia (50%), metabolic and electrolyte abnormalities (42%), uncontrolled hypertension (25%), Sepsis/ infection (23%) and cardiovascular disease (20%). CKD is associated with a wide range of complications like hypertension, anemia, cardiovascular disease, sepsis and poor quality of life. Therapeutic interventions like early detection and prevention of CKD especially in high risk groups like type 2 diabetes, hypertension and age >60 years will help prevent the large scale morbidity and mortality.