Delving into the Latest Updates on Universität Konstanz with Synapse

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The University of Konstanz is an institution of higher education located in the city of Konstanz, Baden-Württemberg, Germany. Being Germany's southernmost university, it is situated just four kilometers from the Swiss border and overlooks Lake Constance. The University of Konstanz has been recognized as one of Germany's elite universities due to its success in all three funding lines of the Excellence Initiative in both 2007 and 2012. The university is consistently ranked among the top 250 globally by the Times Higher Education World University Rankings and was ranked 7th globally in the Times Higher Education 150 under 50 rankings in 2016. It is often referred to as "small Harvard on Lake Constance".

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Nervous System Diseases

Respiratory Diseases

Neoplasms

Small molecule drug

Chemical drugs

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Technology Platform

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Disease Domain	Count

Nervous System Diseases	1
Neoplasms	1

Top 5 Drug Type	Count

Small molecule drug	1
Chemical drugs	1

Top 5 Target	Count

PSMB8(proteasome 20S subunit beta 8)	1
KIF18A(kinesin family member 18A)	1

AbstractPurpose of ReviewApraxia typically involves impairments in gesture production and tool use, affecting daily life activities. This article reviews current conceptualizations and developments in diagnostic and therapy.Recent FindingsApraxia has been studied in various neurological conditions, particularly stroke and dementia, but recent studies show gesturing deficits in psychiatric populations as well. Promising results have emerged from integrative treatment approaches involving intensive practice of gestures or daily activities. However, several reviews have noted the only marginal progress in apraxia therapy research despite new technologies, like virtual reality and brain stimulation, offering fresh opportunities for assessment and therapy.SummaryAdvances in lesion-symptom mapping and connectivity analyses led to more detailed neuroanatomical models emphasizing parallel and gradual processing. These models facilitate the understanding of underlying mechanisms of motor cognitive performance and its decline. Finally, the digital era prompts the need to study digital tool use in apraxia, with initial efforts underway.

01 Mar 2025·International Journal of Applied Positive Psychology

Positive Outcomes of Long-Term Relationship Satisfaction Trajectories in Stable Romantic Couples: A 10-Year Longitudinal Study

Article

Author: Roth, Michelle ; Bodenmann, Guy ; Weitkamp, Katharina ; Landolt, Selina A ; Nussbeck, Fridtjof W

AbstractGrowing evidence challenges the longstanding assumption of a universal decline in relationship satisfaction for all couples by demonstrating variability in the change. However, knowledge about how differential long-term trajectories of relationship satisfaction are associated with positive individual functioning is lacking. Using dyadic latent class growth analysis, we studied long-term trajectories of relationship satisfaction of N = 300 mixed-gender couples over 10 years and examined positive outcomes in latent subgroups. At the final assessment, partners reported on positive outcomes, specifically affect, mental health, and life satisfaction. Depending on their subgroup membership, couples systematically differed: Couples in the subgroup with high initial and relatively stable relationship satisfaction reported the most favorable outcomes—more positive affect, better mental health, and higher life satisfaction—as compared to subgroups with declining and/or lower relationship satisfaction. The findings show the importance of considering the variability in long-term relationship satisfaction trajectories and point to their relevance for positive functioning.

01 Mar 2025·Sensors and Actuators A: Physical

Time-averaged interference fringe analysis: A quantitative study of nanomembrane vibration dynamics

Author: Scheer, Elke ; Fu, Mengqi ; Barth, Valentin ; Dornseiff, Jannik

In this work, we present a method for characterizing nano/micro membrane resonators through the anal. of averaged interference fringes obtained from continuous light measurements.As the membrane vibrates, the interference fringes display blurring and contrast reduction, from which we establish a direct relationship between the vibration amplitude and the blurred area.This method offers a fast and straightforward approach to characterizing membrane vibrations and determining the dispersion relationship.Addnl., it enables the simultaneous extraction of multiple vibrational modes, providing mode numbers and phase differences that can be used to reconstruct dynamic vibration profiles.Its efficiency and broad frequency range make it particularly well-suited for high-frequency applications and rapid data collection.

100 Deals associated with Universität Konstanz

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100 Translational Medicine associated with Universität Konstanz

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Pipeline

Pipeline Snapshot as of 23 Jan 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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2

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