Delving into the Latest Updates on Shandong Bausch & Lomb Freda Pharmaceutical Co. Ltd. with Synapse

Overview

Tags

Eye Diseases

Immune System Diseases

Nervous System Diseases

Small molecule drug

Polymer

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Immune System Diseases	2
Nervous System Diseases	1

Top 5 Drug Type	Count

Small molecule drug	2
Polymer	1

Top 5 Target	Count

nAChRα1/β1/δ/γ(Acetylcholine receptor; alpha1/beta1/delta/gamma)	1
H1 receptor(Histamine H1 receptor)	1

The efficacy of disinfectants to be used in manufacturing environment of medical industry against selected microorganisms on representative surface was evaluated and demonstrated.Efficacy of the disinfectants on representative surface would be evaluated by measuring the mean surviving populations of test microorganisms after exposed to test disinfectants on the surface of a coupon representing a surface present in the manufacturing environment of medical industry.70% Iso-Pr alc. could work against bacteria, 1:32 Spore-klenz could work against bacteria and mold.The effectiveness of disinfectants to different coupons and microorganisms can be not the same.We should choose the proper disinfectants in the manufacturing environments of medical industry.

Zhongguo Yaoxue Zazhi (Beijing, China)

Determination of tetrahydrozoline hydrochloride and its related substances in eye drops by HPLC

Author: Wang, Yuling ; Han, Baoping ; Zhang, Shilei ; Shui, Qinghua ; Yu, Shengmao

A HPLC method for determining the content of tetrahydrozoline hydrochloride and its related substances in eye drops was established.A Diamonsil C₁₈ column (4.6 mm × 150 mm, 5 μm) was used with a mobile phase of methanol-acetate buffer (40:60).The detection was carried out at 235 nm, and flow rate was 1.0 mL/min.The determination limit was 0.22 ng.The standard curve was linear in the range of 9.94-497.0 mg/L^-1 (r = 0.999 9).The aver age recovery was 99.86%, and RSD was 0.23%.The method established was successfully used to determine tetrahydrozoline hydrochloride and its related substances in eye drops.

Shipin Yu Yaopin

Determination of preservative effect on naphazoline hydrochloride and chlorphenamine maleate and vitamin B₁₂ eye drops

Author: Li, Jin ; Bai, Ruowan ; Wang, Lei ; Zhang, Shilei

The bacteriostatic potency of naphazoline hydrochloride and chlorphenamine maleate and Vitamin B12 eye drops were studied.The bacteriostatic potency of the eyedrops was determined by colony counting procedure specified in USP.The bacteriostatic system in the eye drops was stable, and the determination timepoints were conformable to the standard of USP.The method is effective in determining the bacteriostatic potency of ophthalmic preparations

100 Deals associated with Shandong Bausch & Lomb Freda Pharmaceutical Co. Ltd.

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100 Translational Medicine associated with Shandong Bausch & Lomb Freda Pharmaceutical Co. Ltd.

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Pipeline

Pipeline Snapshot as of 17 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Approved

3

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Current Projects

Drug(Targets)	Indications	Global Highest Phase

Sodium Hyaluronate	Osteoarthritis, Knee More	Approved
Pheniramine Maleate ( H1 receptor )	Hypersensitivity More	Approved
Carbachol ( nAChRα1/β1/δ/γ )	Ocular Hypertension More	Approved