Intranasal Fentanyl for Procedural Analgesia in Preterm Infants Undergoing Peripherally Inserted Central Catheter Placement (INFENT PICC): A Feasibility Randomized Controlled Trial
The purpose of this feasibility clinical trial is to explore the role of intranasal fentanyl for pain associated with PICC placement in preterm infants. The primary goals are identifying whether enough infants join the study and complete the study procedures.
A Double-blind, Triple-arm Randomized Controlled Trial of 1% Lidocaine Paracervical Block for Endometrial Biopsy
The objective of this study is to determine whether 1% lidocaine paracervical block reduces pain during endometrial biopsy in comparison to sham paracervical injection with normal saline or no intervention.
The proposed study is a double-blind, triple arm, placebo-controlled randomized controlled trial (RCT). Each participant will be randomly assigned to one of three arms:
1. intervention (paracervical block - 10 cc 1% lidocaine with epinephrine)
2. placebo (10 cc paracervical injection of normal saline)
3. control (gently tapping the cervicovaginal junction with a capped needle)
The primary outcome will be a global pain score, which will be patient-reported by the 100 mm Visual Analogue Scale (VAS) following the procedure.
The LOw PRESSuRE Trial: Laparoscopic Optimization With Pressure Reduction: Effects on Shoulder-tip Pain, Surgical Outcomes and Recovery Enhancement
This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery. Patients will be randomized the to standard group or the intervention group (low pressure) and surgeons will be blinded to study pressure. Data on post operative recovery and pain scores will be recorded for each group.
100 Clinical Results associated with Mount Sinai Hospital (Canada)
0 Patents (Medical) associated with Mount Sinai Hospital (Canada)
100 Deals associated with Mount Sinai Hospital (Canada)
100 Translational Medicine associated with Mount Sinai Hospital (Canada)