Last update 29 Aug 2025

Piston Bio LLC

United States|
www.pistonbio.com

Overview

Tags

Other Diseases
Small molecule drug

Disease domain score
A glimpse into the focused therapeutic areas
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Disease DomainCount
Nervous System Diseases1
Endocrinology and Metabolic Disease1
Top 5 Drug TypeCount
Small molecule drug1
Top 5 TargetCount
A2aR(Adenosine A2a receptor)1

Related

1
Drugs associated with Piston Bio LLC
Istradefylline
Target
A2aR
Mechanism
A2aR antagonists
Active Org.
Kyowa Kirin Co., Ltd.Kyowa Kirin Co., Ltd. [+3]
Originator Org.
Kyowa Kirin Co., Ltd.Kyowa Kirin Co., Ltd.
Active Indication
Parkinson Disease [+3]
Inactive Indication
Drug abuse [+1]
Drug Highest PhaseApproved
First Approval Ctry. / Loc.
Japan
First Approval Date25 Mar 2013
100 Clinical Results associated with Piston Bio LLC
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0 Patents (Medical) associated with Piston Bio LLC
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100 Deals associated with Piston Bio LLC
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100 Translational Medicine associated with Piston Bio LLC
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Pipeline

Pipeline Snapshot as of 03 Sep 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Phase 1
1
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
Istradefylline
 ( A2aR )		Cachexia
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Phase 1
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Profit

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Grant & Funding(NIH)

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Investment

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Financing

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