Investigating the effect of a toothbrush reminder application and a health education video on the oral health of patients undergoing orthodontic treatment.

Start Date03 Feb 2025

Sponsor / Collaborator

Semnan University

IRCT20230515058203N2

/ SuspendedNot ApplicableIIT

Radiographic comparison of the effect of propolis and calcium hydroxide in the treatment of direct pulp cupping

Start Date20 Jan 2025

Sponsor / Collaborator

Semnan University

IRCT20241108063636N1

/ SuspendedPhase 4IIT

Comparison of Dexmedetomidine and Morphine effects for postoperative pain and symptom management following spine surgery: A randomized clinical trial

Start Date20 Jan 2025

Sponsor / Collaborator

Semnan University

100 Clinical Results associated with Semnan University

0 Patents (Medical) associated with Semnan University

11,201

Literatures (Medical) associated with Semnan University

01 Jun 2025·Emission Control Science and Technology

Numerical Investigation of the Effects of the Ammonia Injection Rate Shape and Timing on the Performance of an Ammonia-Hydrogen Dual-Fuel Engine

Author: Aboujafari, Mahdi

Abstract: There is an increasing interest in using ammonia in combustion systems, specifically in internal combustion engines, as an alternative to fossil fuel.It has numerous benefits to manifest as a competent rival against hydrogen.However, an ignition promoter, such as hydrogen addition, is still needed for stable combustion.As the engine using ammonia also suffers from high NOx emissions, in this study, the effects of ammonia injection rate shape and timing on emissions of an ammonia-hydrogen dual-fuel engine were numerically investigated.The base engine was a diesel engine whose intake parameters, such as intake temperature and pressure, were adjusted to adapt to utilize ammonia-hydrogen as fuel.Hydrogen was assumed to be premixed with the intake charge (port injected), and ammonia was directly injected into the cylinder within a definite time.The governing equations were solved by writing a MATLAB code, and the combustion mechanism was implemented in Cantera.The results showed that the ammonia injection with a cubic injection rate shape (increasing the ammonia mass injection rate gradually like a cubic curve) could reduce the in-cylinder pressure by 16.5%.The split ammonia injection between 350 and 370 crank angle degrees (350:360-368:370) produces the least NO and NO₂.This scheme is the best injection strategy since, besides the lowest NO and NO₂ emissions, its peak in-cylinder pressure is only 1% more than the scheme with the least in-cylinder peak pressure (cubic injection rate shape).

01 May 2025·Food Hydrocolloids

Preparation and characterization of zein-kappa carrageenan complex for encapsulation of saffron, and in vitro controlled release study

Author: Asl, Ali Haghighi ; Miao, Song ; Ardestani, Faezeh ; Rafe, Ali

The bioactive compound crocin in saffron is chem. unstable and prone to environmental degradationAn encapsulation system is required to improve its stability, bioavailability, and therapeutic effects.Current methods are often challenged with problems such as rapid release, poor stability, and low encapsulation efficiency.This study provides a new approach for encapsulating saffron extract using complex coacervation method, using zein and kappa carrageenan (KCG) as shell material.The zeta potential and turbidity measurement results indicated that a pH of 3.0 and a zein:KCG ratio of 14:1 were the optimum conditions for zein-KCG complex coacervate formation.The encapsulation efficiency (EE) of freeze-dried saffron extract (FSE) increased under these conditions, and it was found that the EE depended on the ratio between the core (FSE) and the shell (zein:KCG coacervates).The highest encapsulation efficiency, 71.53 ± 2.76%, was obtained at a core-to-shell ratio of 1:2.The size of microcapsules increased from 1.25 μm to 2.82 μm after crosslinking with tannic acid (TA).The thermal properties of the microcapsules improved with crosslinking with TA, and FTIR anal. provides further evidence of electrostatic interactions between zein and KCG and hydrogen bond formation between FSE and the shell.Addnl., the microcapsules (non-crosslinked and crosslinked) remained stable in acidic conditions and demonstrated slow release in the gastrointestinal system.

01 Apr 2025·Journal of Molecular Structure

New dinuclear Schiff base nickel complex: Investigation of intermolecular interactions via theoretical calculations, molecular docking studies and ADMET profiling approaches survey

Author: Kubicki, Maciej ; Salehi, Mehdi ; Parvarinezhad, Sakineh

Herein we report the results of our exploration of a Schiff base ligand derived from 2-amino-2-methyl-1-propanol and 2,5-dihydroxybenzaldehyde which is used to synthesize and characterize a Ni(II) complex [Ni^II₂LH₂(CH₃OH)₂(CH₃COO)₂].The IR spectra and electron transfer spectroscopy have been executed to justify the structure of the compoundsThe solid-state structure of the [Ni^II₂LH₂(CH₃OH)₂](CH₃COO)₂] complex has also been investigated by single crystal X-ray diffraction.Ni(II) center is hexa-coordinate with imine-N, phenolate -O, propane-OH of the ligand, two CH₃OH solvents, and two CH₃COO mols. occupying the coordination sphere forming a distorted octahedral geometry.The Cyclic voltammetry of the complex in DMSO solvent revealed the electronic effects of the groups on the redox potential.By employing computational methods, the ligand and [Ni^II₂LH₂(CH₃OH)₂](CH₃COO)₂] structures were optimized using common software (Gaussian 09) with the basis set of B3LYP 6-311 G Upon completion of the optimization procedure, essential phys. characteristics for validation and correlation were derived.Intermol. exchanges in the solid states were analyzed through the Hirshfeld surface.Furthermore, the investigation extends to mol. docking, the main goal of mol. docking which is to study their biol. efficacy, potential properties, and interactions survey of specific protein structures (1BG1 and CoV-2 for PDB protein ID: 6Y2F) with ligand and [Ni^II₂LH₂(CH₃OH)₂](CH₃COO)₂] structures.Also, by ADMET anal., it was found that the studied ligand follows Lipinski′s law of five wells, and based on bioactivity valuation, it has favorable drug-likeness properties.The obtained results may be more useful in drug design and its application to inhibit cancer and SARS-CoV-2.

100 Deals associated with Semnan University

100 Translational Medicine associated with Semnan University

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