
| Disease Domain | Count |
|---|---|
| Nervous System Diseases | 3 |
| Endocrinology and Metabolic Disease | 3 |
| Immune System Diseases | 1 |
| Top 5 Drug Type | Count |
|---|---|
| Recombinant protein | 1 |
| Synthetic peptide | 1 |
| Peptide Hormone | 1 |
| Monoclonal antibody | 1 |
| Top 5 Target | Count |
|---|---|
| AMYR x CALCR x GLP-1R | 1 |
| AMYR x GLP-1R | 1 |
| INSR(Insulin receptor) | 1 |
| IL-6(Interleukin-6) | 1 |
Target |
Mechanism INSR agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target |
Mechanism AMYR agonists [+2] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseNDA/BLA |
First Approval Ctry. / Loc.- |
First Approval Date- |
Target |
Mechanism AMYR agonists [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date- |
Start Date20 Feb 2024 |
Sponsor / Collaborator |
Start Date15 Aug 2023 |
Sponsor / Collaborator |
Start Date27 Nov 2019 |
Sponsor / Collaborator [+1] |


| Drug(Targets) | Indications | Global Highest Phase |
|---|---|---|
Isophane Protamine Human Insulin(Novo Nordisk A/S) ( INSR ) | Diabetes Mellitus More | Approved |
Ziltivekimab ( IL-6 ) | Chronic heart failure More | Phase 3 |
Semaglutide/Cagrilintide ( AMYR x CALCR x GLP-1R ) | Obesity More | Phase 3 |
Zenagamtide ( AMYR x GLP-1R ) | Sleep Apnea, Obstructive More | Phase 3 |





