Effectiveness of Post Operative Analgesia with Intraoperative Pectoral Nerve block versus Serratus Anterior Block in patients undergoing Modified Radical Mastectomy (MRM) for breast cancer -A Randomized Control Trial - NIL

Start Date26 Aug 2024

Sponsor / Collaborator

Institute of Medical Sciences & SUM Hospital

CTRI/2024/08/072214 / Not yet recruitingNot ApplicableIIT

Effect of preoperative informational video onperioperative anxiety in patients undergoingsurgery under general anesthesia-A Randomized control study - NIL

Start Date19 Aug 2024

Sponsor / Collaborator

Institute of Medical Sciences & SUM Hospital

CTRI/2024/08/071849 / Not yet recruitingPhase 4IIT

Comparison of sugammadex and neostigmine for reversal of vecuronium induced neuromuscular blockade in elderly patients - NIL

Start Date15 Aug 2024

Sponsor / Collaborator

Institute of Medical Sciences & SUM Hospital

100 Clinical Results associated with Institute of Medical Sciences & SUM Hospital

0 Patents (Medical) associated with Institute of Medical Sciences & SUM Hospital

285

Literatures (Medical) associated with Institute of Medical Sciences & SUM Hospital

01 Nov 2024·CNS & Neurological Disorders - Drug Targets

Emerging Treatments for Subarachnoid Hemorrhage

Review

Author: Nelson, Jayson R. ; Winterton, Candace ; Cole, Kyril L. ; Kundu, Mrinmoy ; Findlay, Matthew C. ; Tenhoeve, Samuel ; Lucke-Wold, Brandon

:The current landscape of therapeutic strategies for subarachnoid hemorrhage (SAH), a significant adverse neurological event commonly resulting from the rupture of intracranial aneurysms, is rapidly evolving. Through an in-depth exploration of the natural history of SAH, historical treatment approaches, and emerging management modalities, the present work aims to provide a broad overview of the shifting paradigms in SAH care. By synthesizing the historical management protocols with contemporary therapeutic advancements, patient-specific treatment plans can be individualized and optimized to deliver outstanding care for the best possible SAH-related outcomes.

01 Oct 2024·Hepatology International

Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN)

Review

Author: Panda, Kalpana ; Shankar, Sahana ; Dhawan, Anil ; Alam, Seema ; Sathiyasekaran, Malathi ; Pandey, Snehavardhan ; Deep, Akash ; Khanna, Rajeev ; Kale, Pratibha ; Koul, Roshan Lal ; Ramakrishna, Somashekara Hosaagrahara ; Sood, Vikrant ; Malhotra, Smita ; Malik, Rohan ; Pawaria, Arti ; Gautam, Vipul ; Mohan, Neelam ; Nagral, Aabha ; Sarin, Shiv Kumar ; Lal, Bikrant Bihari ; Rela, Mohamed ; Srivastava, Anshu ; Kumar, Karunesh ; Maria, Arjun ; Sivaramakrishnan, Viswanathan M ; Sarma, Moinak Sen ; Samyn, Marianne ; Agarwal, Sajan ; Ravindranath, Aathira ; Desai, Moreshwar S ; Yachha, Surender Kumar ; Deswal, Shivani ; Desai, Moreshwar S. ; Kumar, Aditi ; Maiwall, Rakhi ; Bavdekar, Ashish ; Sivaramakrishnan, Viswanathan M. ; Lal, Sadhna ; Gopan, Amrit ; Dheivamani, Nirmala ; Peethambaran, Maya ; Sindwani, Gaurav ; Borkar, Vibhor ; Upadhyay, Piyush ; Dhaliwal, Maninder

Timely diagnosis and management of pediatric acute liver failure (PALF) is of paramount importance to improve survival. The Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition invited national and international experts to identify and review important management and research questions. These covered the definition, age appropriate stepwise workup for the etiology, non-invasive diagnosis and management of cerebral edema, prognostic scores, criteria for listing for liver transplantation (LT) and bridging therapies in PALF. Statements and recommendations based on evidences assessed using the modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) system were developed, deliberated and critically reappraised by circulation. The final consensus recommendations along with relevant published background information are presented here. We expect that these recommendations would be followed by the pediatric and adult medical fraternity to improve the outcomes of PALF patients.

28 Sep 2024·IP International Journal of Medical Microbiology and Tropical Diseases

Prevalence -lactam resistant Pseudomonas aeruginosa strains isolated from chronic supportive otitis media infections: A single center survey in Eastern India

Author: Singhsamanta, Debidatta ; Das, Saumya Ranjan ; Rath, Shakti ; Dubey, Debasmita

is a pernicious opportunistic bacterium causing several human infections due to its ubiquitous presence and adaptability to various environmental conditions. Primarily, β-lactamase producing strains are the most prevalent ones, especially chronic suppurative otitis media (CSOM) infections. This research was conducted to find the pervasiveness of β-lactam producing strains in CSOM patients attending a multispeciality hospital in Eastern India.The 100 swabs were collected from CSOM patients, of which 76 were males (mean age 46) and 24 were females (mean age 41); strains were isolated and identified using routine microbiological methods. Kirby-Bauer method was employed to determine the antibiotic sensitivity of the isolated strains. Virulence tests like the swarming mortality test, biofilm formation assay, haemolysis assay, protease and pyocyanin production assay were conducted to detect the presence of various inherent virulence characters qualitatively. Both phenotypic and genotypic determination of β-lactamase-producing strains were confirmed by disc diffusion test and PCR methods.Out of 100 samples, 67 strains were isolated, and all were motile. All strains tested positive for pyocyanin and haemolysis enzymes. Most strains had the biofilm formation capacity and release of protease enzyme. Most strains were multidrug-resistant, particularly to the β-lactam group of antibiotics. Nearly 80% of strains harboured all four classes of β-lactamase genes, producing enzymes like ESBLs, MBLs, AmpC and carbapenemase. The β-lactamase genes and the inherent virulence factors that increase the infectiousness and adaptability of strains are significantly correlated. Immediate modified antibiotic policy should be employed to overcome this issue of multidrug resistance.

100 Deals associated with Institute of Medical Sciences & SUM Hospital

100 Translational Medicine associated with Institute of Medical Sciences & SUM Hospital

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