[Translation] Single-center, open, randomized, single-dose, double-period, double-crossover postprandial bioequivalence study of acetaminophen and ibuprofen tablets in healthy subjects
以长春澜江医药科技有限公司提供的对乙酰氨 基 酚 布 洛 芬 片 ( 每 片 含 对 乙 酰 氨 基 酚 250mg , 布 洛 芬 125mg ) 与Glaxosmithkline Consumer Healthcare Holdings US LLC持证的对乙酰氨基酚布洛芬片(每片含对乙酰氨基酚250mg,布洛芬125mg;商品名:Advil Dual Action With Acetaminophen®),比较两制剂在餐后给药条件下,在健康成年人群中吸收程度和速度的差异,评价其生物等效性。并评估两制剂的安全性和耐受性。
[Translation] Take acetaminophen ibuprofen tablets provided by Changchun Lanjiang Pharmaceutical Technology Co., Ltd. (each tablet contains acetaminophen 250mg, ibuprofen 125mg) and acetaminophen ibuprofen licensed by Glaxosmithkline Consumer Healthcare Holdings US LLC Tablets (each containing 250mg of acetaminophen and 125mg of ibuprofen; trade name: Advil Dual Action With Acetaminophen®), comparing the difference in the degree and speed of absorption of the two preparations in healthy adults under the condition of postprandial administration, evaluate its bioequivalence. And evaluate the safety and tolerability of the two preparations.