复方罗红霉素片治疗轻中度急性下呼吸道细菌感染伴有痰液粘稠的随机双盲双模拟阳性药平行对照多中心临床试验
[Translation] A randomized, double-blind, double-dummy, positive drug parallel-controlled multicenter clinical trial of compound roxithromycin tablets in the treatment of mild to moderate acute bacterial infection of the lower respiratory tract with thick sputum
以罗红霉素为对照,进一步评价复方罗红霉素片治疗轻、中度急性下呼吸道细菌感染伴有痰液粘稠的安全性和有效性
[Translation] Taking roxithromycin as a control, the safety and efficacy of compound roxithromycin tablets in the treatment of mild to moderate acute lower respiratory tract bacterial infection with thick sputum were further evaluated
多中心、随机、阳性药平行对照评价复方罗红霉素分散片治疗下呼吸道感染痰液粘稠的有效性和安全性临床研究
[Translation] Clinical study on the efficacy and safety of compound roxithromycin dispersible tablets in the treatment of lower respiratory tract infection with thick sputum
评价复方罗红霉素分散片治疗下呼吸道感染伴痰液粘稠的有效性与安全性
[Translation] To evaluate the efficacy and safety of compound roxithromycin dispersible tablets in the treatment of lower respiratory tract infection with thick sputum
[Translation] Pharmacokinetic study of compound roxithromycin dispersible tablets in humans
考察受试制剂中两种主药(罗红霉素与盐酸氨溴索)的体内吸收程度和吸收速度是否与单方有显著性差异,并考察罗红霉素与盐酸氨溴索联合使用是否有药物相互作用。考察复方罗红霉素分散片多次给药后的稳态平均血药浓度(Cav),达到稳态时药物谷、峰浓度,及稳态血药浓度的波动系数(DF),多次给药是否存在药物蓄积作用。
[Translation] Investigate whether the in vivo absorption degree and absorption speed of the two main drugs (roxithromycin and ambroxol hydrochloride) in the test preparation are significantly different from those of the single prescription, and whether the combined use of roxithromycin and ambroxol hydrochloride has any significant effect. medicine interactions. The steady-state average plasma concentration (Cav) of compound roxithromycin dispersible tablets after multiple administrations, the drug trough and peak concentrations when reaching steady state, and the fluctuation coefficient (DF) of steady-state plasma concentration were investigated. Whether the drug has drug accumulation effect.
100 Clinical Results associated with Hefei Chuandi Pharmaceutical Technology Co., Ltd.
0 Patents (Medical) associated with Hefei Chuandi Pharmaceutical Technology Co., Ltd.
100 Deals associated with Hefei Chuandi Pharmaceutical Technology Co., Ltd.
100 Translational Medicine associated with Hefei Chuandi Pharmaceutical Technology Co., Ltd.