Anhui Pioneer Pharmaceutical Co. Ltd.

The aim of this study was to investigate the pharmacokinetic characteristics of clindamycin palmitate hydrochloride granules (75 mg/5 ml calculated as clindamycin (C18H33ClN2O5S)) and clindamycin palmitate hydrochloride granules (75 mg calculated as clindamycin (C18H33ClN2O5S)) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single oral administration on an empty stomach or after a meal. Clindamycin palmitate hydrochloride granules (Cleocin Pediatric®, 75 mg/5 ml calculated as clindamycin (C18H33ClN2O5S) produced by Pharmacia & Upjohn Company LLC were used as the reference preparation. The pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ of the test preparation were compared with those of the reference preparation, and the bioequivalence of the test preparation with the reference preparation was evaluated.

This study aimed to investigate the pharmacokinetic characteristics of oxcarbazepine tablets (0.3 g) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single oral administration on an empty stomach or after a meal in healthy subjects; using oxcarbazepine tablets (Trilep®, 0.3 g) produced by Novartis Farma S.p.A. as the reference preparation, the pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ of the two preparations were compared, and the bioequivalence of the two preparations in humans was evaluated.

This study aimed to study the pharmacokinetic characteristics of trazodone hydrochloride tablets (50 mg) developed and produced by Anhui Pioneer Pharmaceutical Co., Ltd. after single oral administration on an empty stomach or after a meal; using trazodone hydrochloride tablets (RESLIN®, 50 mg) licensed and produced by Olganon Co., Ltd. as the reference preparation, the pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ of the two preparations were compared, and the bioequivalence of the two preparations in humans was evaluated.