Delving into the Latest Updates on Beijing Yiling Pharmaceutical Co., Ltd. with Synapse

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Otorhinolaryngologic Diseases

Immune System Diseases

Respiratory Diseases

Herbal medicine

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Disease Domain	Count

Immune System Diseases	1
Infectious Diseases	1

Top 5 Drug Type	Count

Herbal medicine	1

To preliminarily evaluate the effectiveness of Yuping Tongqiao Tablets in treating persistent allergic rhinitis (lung and spleen deficiency syndrome); To explore the action characteristics and advantageous dose of Yuping Tongqiao Tablets in treating persistent allergic rhinitis; To evaluate the safety of Yuping Tongqiao Tablets in patients with persistent allergic rhinitis; To provide a basis for further clinical research design.

Start Date24 Feb 2021

Sponsor / Collaborator

Beijing Yiling Pharmaceutical Co., Ltd.

[+1]

CTR20140520

/ CompletedPhase 2

评价连花定喘片治疗支气管哮喘慢性持续期有效性和安全性随机、双盲、平行对照、多中心IIb期临床研究

[Translation] A randomized, double-blind, parallel-controlled, multicenter phase IIb clinical study to evaluate the efficacy and safety of Lianhua Dingchuan tablets in the treatment of chronic persistent bronchial asthma

探索连花定喘片对支气管哮喘慢性持续期的症状改善作用；对支气管哮喘慢性持续期热哮证的改善作用；探索连花定喘片治疗支气管哮喘慢性持续期（热哮证）的合理剂量；观察连花定喘片的安全性及不良反应。

[Translation]

To explore the symptom-improving effect of Lianhua Dingchuan tablets on chronic persistent stage of bronchial asthma; to explore the improving effect on hot asthma syndrome in chronic persistent stage of bronchial asthma; to explore the reasonable dosage of Lianhua Dingchuan tablets in the treatment of chronic persistent stage of bronchial asthma (hot asthma syndrome); to observe the safety and adverse reactions of Lianhua Dingchuan tablets.

Start Date29 Sep 2014

Sponsor / Collaborator

Beijing Yiling Pharmaceutical Co., Ltd.

[+1]

100 Clinical Results associated with Beijing Yiling Pharmaceutical Co., Ltd.

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0 Patents (Medical) associated with Beijing Yiling Pharmaceutical Co., Ltd.

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10

Literatures (Medical) associated with Beijing Yiling Pharmaceutical Co., Ltd.

01 Sep 2012·Journal of Asian Natural Products ResearchQ4 · MEDICINE

Total synthesis of epiberberine

Q4 · MEDICINE

Article

Author: Zhao, Shao-Hua ; Tu, Peng-Fei ; Wang, Hong-Tao ; Liang, Jun-Qing ; Zhang, Hao ; Lu, Zi-Ming

Epiberberine, a natural bioactive protoberberine alkaloid, was totally synthesized in short, convenient and low-cost, four-step reactions including cyclization, condensation, reduction, and ring-closing, with an overall yield of 26.1%.

Records of Natural Products

Three new chemical constituents of Dryopteris crassirhizoma Nakai in Lianhua Qingwen capsule and investigation on their antiviral potential based on 3CL hydrolase of SARS-CoV-2

Author: Wang, Tongxing ; Zhang, Chuangfeng ; Hou, Bin ; Shen, Shuo ; Zhang, Yifu ; Jia, Zhenhua ; Bi, Dan ; He, Fengjun ; Sun, Yunbo ; Tian, Ya

Three new chromone glycosides, named 2-methyl-5-hydroxyl-4-chromone-7-O-β-D-glucuronide (1), 2-ethyl-5-hydroxyl-4-chromone-7-O-β-D-glucuronide (2) and 1-acetyl-3-C-β-D-glucopyranosyl-5-methylphloroglucinyl-6-O-β-D-glucopyranoside (6), together with eight known compounds were isolated from the water extract of Dryopteris crassirhizoma Nakai,and the water extract preparation process is consistent with Lianhua Qingwen capsule.All the chem. structures of new compounds were characterized by 1D and 2D NMR spectra as well as high resolution mass and IR spectra.The chem. structures of known compounds were characterized by NMR spectra along with comparison of their spectroscopic data with those reported in the literature.The binding ability of these compounds to 3CL hydrolase of SARS-COV-2 was evaluated by mol. docking.The results showed that the chromone glycosides with glucuronic acid fragment had good docking effect with 3CL hydrolase and this indicated the chromone glucuronides could be further studied as potential antiviral compounds

Zhongguo Yiyao Daobao

Optimization of spraying dry process of licorice extract by orthogonal experiment

Author: Lu, Ziming ; Liang, Junqing ; Yu, Xianghong ; Liu, Xiaoyan ; Wang, Chao ; Guan, Hongfeng

The spraying dry process of Licorice extract was investigated.The effects of inlet temperature, outlet temperature and sp. gr. of the extract on the spraying dry process of Licorice extract were inspected by L₉(3⁴) orthogonal experiment with powder amount, Liquiritin and Glycyrrhizic acid contents as well as moisture content as the indexes.The optimal spraying dry process was: inlet temperature as 180 degree C, outlet temperature as 90 degree C and sp. gr. as 1.15.The optimal spraying dry process is rational, stable and provided experiment base for industrial production

100 Deals associated with Beijing Yiling Pharmaceutical Co., Ltd.

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100 Translational Medicine associated with Beijing Yiling Pharmaceutical Co., Ltd.

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Pipeline

Pipeline Snapshot as of 26 May 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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