Guangdong Jincheng Pharmaceuticals Co. Ltd.

Main objectives: 1. To study the pharmacokinetic behavior of cefdinir in healthy Chinese subjects after a single oral administration of the test formulation of cefdinir dry suspension (specification: 250mg/5ml, provided by Guangdong Jincheng Jinsu Pharmaceutical Co., Ltd.) and the reference formulation (specification: 250mg/5ml, licensee: Sandoz Inc.) on an empty stomach, and to evaluate the bioequivalence of the two formulations after oral administration on an empty stomach. 2. To study the pharmacokinetic behavior of cefdinir in healthy Chinese subjects after a single oral administration of the test formulation of cefdinir dry suspension (specification: 250mg/5ml, provided by Guangdong Jincheng Jinsu Pharmaceutical Co., Ltd.) and the reference formulation (specification: 250mg/5ml, licensee: Sandoz Inc.) after a meal, and to evaluate the bioequivalence of the two formulations after oral administration on a empty stomach. Secondary objectives: To evaluate the safety of the test formulation and the reference formulation of cefdinir dry suspension in healthy Chinese subjects after a single oral administration on an empty stomach and after a meal.

The human pharmacokinetic study was conducted using the certified penicillin V potassium tablets produced by Guangdong Jincheng Jinsu Pharmaceutical Co., Ltd. as the test preparation, and the penicillin V potassium tablets produced by Sandoz GmbH as the reference preparation.

The main purpose of the study is to study the pharmacokinetics of the test preparation pregabalin capsule (specification: 150 mg, produced by Shanghai Jincheng Suzhi Pharmaceutical Co., Ltd., provided by Guangdong Jincheng Jinsu Pharmaceutical Co., Ltd.) and the reference preparation pregabalin capsule (Lyrica®, specification: 150 mg; produced by Pfizer Manufacturing Deutschland GmbH, Betriebsstatte Freiburg, licensee is Pfizer Limited) in healthy adult subjects after a single oral administration in the fasting and fed state, and to evaluate the bioequivalence of the two preparations in the fasting and fed state. Secondary purpose of the study: to study the safety of the test preparation pregabalin capsule and the reference preparation pregabalin capsule (Lyrica®) in healthy adult subjects.