Last update 23 Jan 2025

caspase 8 x IL-1β x APRIL x TNF-α x IFNγ

Basic Info

Related Targets
caspase 8IL-1βAPRIL[+2]

Related

1
Drugs associated with caspase 8 x IL-1β x APRIL x TNF-α x IFNγ
Edratide
Target
APRIL x IFNγ x IL-1β x TNF-α x caspase 8
Mechanism
APRIL inhibitors [+5]
Active Org.
Weizmann Institute of ScienceWeizmann Institute of Science
Originator Org.
Weizmann Institute of ScienceWeizmann Institute of Science
Active Indication
Systemic Lupus Erythematosus
Inactive Indication
Sjogren's Syndrome
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
1
Clinical Trials associated with caspase 8 x IL-1β x APRIL x TNF-α x IFNγ
NCT00203151
/ TerminatedPhase 2
A Multi-National, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose, Parallel Group Study to Assess the Efficacy, Tolerability and Safety of Edratide for Subcutaneous Injection in Systemic Lupus Erythematosus (SLE)
100 Clinical Results associated with caspase 8 x IL-1β x APRIL x TNF-α x IFNγ
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100 Translational Medicine associated with caspase 8 x IL-1β x APRIL x TNF-α x IFNγ
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0 Patents (Medical) associated with caspase 8 x IL-1β x APRIL x TNF-α x IFNγ
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