Last update 23 Jan 2025

DHCR24

Basic Info

Synonyms
24-dehydrocholesterol reductase, 3-beta-hydroxysterol Delta-24-reductase, DCE
+ [5]
Introduction
Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:25637936, PubMed:22178193). In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress (PubMed:11007892, PubMed:22010141). Also protects against amyloid-beta peptide-induced apoptosis (PubMed:11007892).

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