Last update 08 May 2025

GPX4 x Nrf2 x PGK1

Basic Info

Related Targets
GPX4Nrf2PGK1

Related

1
Drugs associated with GPX4 x Nrf2 x PGK1
Di-Dang-Tang
Target
GPX4 x Nrf2 x PGK1
Mechanism
GPX4 agonists [+2]
Active Org.
Nanjing University of Chinese MedicineNanjing University of Chinese Medicine
Originator Org.
Nanjing University of Chinese MedicineNanjing University of Chinese Medicine
Active Indication
Dementia, Vascular
Inactive Indication-
Drug Highest PhasePreclinical
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
100 Clinical Results associated with GPX4 x Nrf2 x PGK1
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100 Translational Medicine associated with GPX4 x Nrf2 x PGK1
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0 Patents (Medical) associated with GPX4 x Nrf2 x PGK1
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1
Literatures (Medical) associated with GPX4 x Nrf2 x PGK1
01 Mar 2025International Immunopharmacology
Di-Dang-Tang suppresses ferroptosis in the hippocampal CA1 region by targeting PGK1/NRF2/GPX4 signaling pathway to exert neuroprotection in vascular dementia

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