Last update 01 Nov 2024

mGluR7

Basic Info

Synonyms
GLUR7, glutamate metabotropic receptor 7, glutamate receptor, metabotropic 7
+ [7]
Introduction
G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (PubMed:33500274). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (PubMed:9473604).

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