Last update 08 May 2025

NLK x hMELK

Basic Info

Related Targets
NLKhMELK

Related

1
Drugs associated with NLK x hMELK
OTS-167
Target
NLK x hMELK
Mechanism
MELK inhibitors [+1]
Active Org.
OncoTherapy Science, Inc.OncoTherapy Science, Inc. [+1]
Originator Org.
OncoTherapy Science, Inc.OncoTherapy Science, Inc.
Active Indication
Advanced breast cancer [+3]
Inactive Indication
Acute Lymphoblastic Leukemia [+7]
Drug Highest PhasePhase 1
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
3
Clinical Trials associated with NLK x hMELK
JPRN-jRCT2031230090
/ RecruitingPhase 1IIT
A Phase I Study of OTS167PO, a MELK inhibitor, to Evaluate Safety, Tolerability and Pharmacokinetics in Patients with Advanced Breast Cancer and Dose-Expansion Study in Patients with Triple Negative Breast Cancer. - OTS1070103
NCT02926690
/ Active, not recruitingPhase 1
A Phase I Study of OTS167PO, a MELK Inhibitor, to Evaluate Safety, Tolerability and Pharmacokinetics in Patients with Advanced Breast Cancer and Dose-Expansion Study in Patients with Triple Negative Breast Cancer
ACTRN12616000043437
/ CompletedPhase 1IIT
A phase 1, randomised, placebo-controlled, double-blind, cross-over study to evaluate systemic bioavailability of oral OTS167 under fed and fasting conditions in healthy adult subjects.
100 Clinical Results associated with NLK x hMELK
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100 Translational Medicine associated with NLK x hMELK
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0 Patents (Medical) associated with NLK x hMELK
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