Last update 21 Mar 2024

CD3ζ x EGFR x CD19 x 4-1BB

CD247 molecule x Epidermal growth factor receptor erbB1 x B-lymphocyte antigen CD19 x Tumor necrosis factor receptor superfamily member 9

Basic Info

Related Targets
CD3ζEGFRCD19[+1]

Related

1
Drugs associated with CD3ζ x EGFR x CD19 x 4-1BB
Autologous Anti-CD19CAR-4-1BB-CD3zeta-EGFRt-expressing T Lymphocytes(Fred Hutchinson Cancer Center)
Target
4-1BB x CD19 x CD3ζ x EGFR
Mechanism
4-1BB inhibitors [+5]
Active Org.-
Originator Org.
Fred Hutchinson Cancer Center
Active Indication-
Inactive Indication
Acute Lymphoblastic Leukemia [+2]
Drug Highest PhasePending
First Approval Ctry. / Loc.-
First Approval Date20 Jan 1800
1
Clinical Trials associated with CD3ζ x EGFR x CD19 x 4-1BB
NCT01865617 / CompletedPhase 1/2IIT
Phase I/II Study of Immunotherapy for Advanced CD19+ Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia/Lymphoma and Non-Hodgkin Lymphoma With Defined Subsets of Autologous T Cells Engineered to Express a CD19-Specific Chimeric Antigen Receptor
100 Clinical Results associated with CD3ζ x EGFR x CD19 x 4-1BB
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100 Translational Medicine associated with CD3ζ x EGFR x CD19 x 4-1BB
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0 Patents (Medical) associated with CD3ζ x EGFR x CD19 x 4-1BB
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