Synonyms ABC36, ABCC8, ATP binding cassette subfamily C member 8 + [12] |
Introduction Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release. |
Target |
Mechanism PRKAB1 activators [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date31 Jul 2000 |
Target |
Mechanism PPARγ antagonists [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date16 Jun 1999 |
Target |
Mechanism SUR1 inhibitors |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date30 Nov 1995 |
Start Date01 Jan 2025 |
Sponsor / Collaborator |
Start Date26 Oct 2024 |
Sponsor / Collaborator |
Start Date15 Jul 2024 |
Sponsor / Collaborator- |