Yes, celecoxib and tramadol, marketed under the brand name Seglentis, received FDA approval on October 15, 2021. This combination medication is used in adults for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation. Tramadol is an opioid pain medication that acts on the central nervous system to relieve pain. When combined, these two drugs offer a potent solution for managing acute pain.
Celecoxib and tramadol are used when other pain medications are ineffective or cannot be used. This combination can manage acute pain severe enough to require an opioid analgesic. It is taken orally, usually in the form of a tablet containing 56 mg of celecoxib and 44 mg of tramadol.
The typical dosage for adults is two tablets taken orally every 12 hours as needed for pain. It is important to follow the prescription guidelines closely to avoid the risk of serious side effects, including respiratory depression.
Serious Side Effects
Seek immediate medical attention if you experience any of the following:
Common Side Effects
Celecoxib and tramadol can interact with many medications, including antidepressants, benzodiazepines, other NSAIDs, other opioids, and medications to treat or prevent blood clots. Always inform your doctor about all the medications you are taking to avoid potentially dangerous interactions.
Store celecoxib and tramadol at room temperature, away from moisture and heat. Keep track of your medication and dispose of any leftover medicine through a drug take-back program or by mixing it with cat litter or coffee grounds in a sealed plastic bag and throwing it in the trash.
Celecoxib and tramadol (Seglentis) is a powerful combination for managing severe pain when other treatments are insufficient. Approved by the FDA on October 15, 2021, it combines the anti-inflammatory properties of celecoxib with the pain-relieving effects of tramadol. It is crucial to follow the prescribed dosage and guidelines closely, be aware of potential side effects, and communicate with your healthcare provider about any other medications you are taking to ensure safe and effective use.
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