Utilize Synapse Database to Explore Translational Medicine!

The Synapse Database for Translational Medicine is now live, come and experience it!

What are the characteristics of the Synapse database in transforming medicine?

Comprehensive Data Coverage 

Utilizing AI technology and an expert team, the Synapse database integrates the latest research materials from top global research institutions, medical facilities, and academic journals into translational medicine. Currently, it primarily encompasses data from 11 leading journals (such as Nature, Cell, Lancet, JMC, etc.) and abstracts from over 10 prestigious conferences (including ASCO, AACR, EULAR, ASH, and others).

Accurate Literature Search

Through advanced search algorithms, literature from around the globe can be rapidly categorized into 12 major topics including epidemiology, pathogenesis, targets/biomarkers, etc., and it extracts key information such as drugs, targets, indications, drug types, institutions, technologies, and research highlights. This enables quick localization and in-depth exploration of literature related to translational medicine.

Intelligent Analytical Views 

Provide real-time data analysis tools to help users gain insights into research trends and grasp industry dynamics. Aggregate the number of medical literature publications by years of issuance, ranking top targets, indications, and drug types to understand research trends.

Taking obesity as an example, one can observe that GLP-1R treatments for obesity have been quite popular over the past three years, and as of 2023, there are still preclinical studies ongoing. Additionally, new potential targets have emerged, such as PSD95, APOL6, etc.

Based on the number of published papers in various topics of translational medicine, conduct a cross-analysis of targets, indications, and drug types to understand research directions. Taking siRNA as an example, its research scope has already spanned multiple therapeutic areas.

Based on the number of translational medicine publications, a ranking of research institutions was conducted to identify current leaders in the field. Taking Alzheimer's disease as an example, Roche has conducted extensive basic research on Alzheimer's disease and has published numerous studies on disease mechanisms and targets.

Efficient Retrieval Methods

The Translational Medicine Data Section supports searches based upon various entity fields, spanning the T0 to T3 stages of translational phases. In addition, we offer search capabilities for conferences from previous years, as well as filter options, view modes, translation services, and highlights summaries.

Click on the image below to go directly to the Translational Medicine search interface.

Application Scenarios

1.New Target Discovery: Rapid identification of potential new targets using translational medicine data.

Latest Potential Targets in ALS Research: Enter ALS in the indications section of the translational medicine category. Select the topic "Targets/Biomarkers." A total of 67 translational medicine publications were found. Click search to access all publication details.

2. Discovering New Pathogenic Mechanisms for Diseases: Understanding the fundamental causes of diseases through basic research to provide new ideas for treatment.

Research on the Pathogenesis of Non-Small Cell Lung Cancer: In the translational medicine section under the indication for non-small cell lung cancer, the theme "pathogenic mechanism" has been highlighted, resulting in the retrieval of 30 translational medicine literature articles.

3. Conduct in-depth research on the structure and function of targets.

PD-1 Structural and Functional Research: Enter PD-1 at the target section of the translational medicine segment, select Structural Biology as the focus, and search. The system will automatically provide the translation of the title and abstract of a research article. Clicking on the title will allow you to jump to and review the details of the article.

4. Search for the Latest Preclinical Research: Providing pharmaceutical R&D personnel and physicians with up-to-date clinical research information to aid clinical decision-making.

AACR 2024 Preclinical Research: Click on "Drug Discovery/Preclinical" in the translational medicine section, select AACR 2024 at the academic conference section, and click search to instantly find 795 pieces of translational medical literature.

5.Technical Insight: Mining the Cutting-Edge Technologies in New Drug Development

Recent one-month technology literature mining: Click on "New Technology" in the section of Translational Medicine, select a publication date within one month, and hit search to instantly locate 668 pieces of translational medicine literature.

6.Research on Disease Epidemic Trends: Epidemiological studies can reveal the potential causes and risk factors of diseases, providing direction for scientific research efforts.

Experience the Synapse database now and embark on your journey into translational medicine!