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Last update 08 May 2025

Asteatosis cutis

Last update 08 May 2025

Basic Info

Synonyms

Asteatosis cutis, Asteatosis cutis (disorder), Skin xerosis

+ [10]

Introduction-

Drugs associated with Asteatosis cutis

Aprepitant

Target

NK1R

Mechanism

NK1R antagonists

Active Org.

CSPC ZhongNuo Pharmaceutical (Shijiazhuang) Co. Ltd. [+6]

Originator Org.

Merck Sharp & Dohme Corp.

Active Indication

Postoperative Nausea and Vomiting [+7]

Inactive Indication

Acute Myeloid Leukemia [+14]

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

United States

First Approval Date26 Mar 2003

Mucopolysaccharide Polysulfate

Target

factor Xa

Mechanism

factor Xa inhibitors

Active Org.

Maruho Co., Ltd. [+1]

Originator Org.

Maruho Co., Ltd.

Active Indication

Asteatosis cutis [+12]

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

Japan

First Approval Date01 Oct 1954

Clinical Trials associated with Asteatosis cutis

ACTRN12624001057572

/ Not yet recruitingNot ApplicableIIT

Alterations in skin hydration, moisture and genomic in adult patients with dry skin conditions following daily oral palm tocotrienol and squalene (STGAIATM) supplementation

Start Date04 Nov 2024

Sponsor / Collaborator

Monash University Malaysia Sdn. Bhd.

[+1]

CTRI/2024/06/069649

/ Not yet recruitingNot ApplicableIIT

Single arm clinical study to evaluate role narikel tail padabhyanga as upakram in dincharya to prevent seasonal padadari w.r.t. to hemant rutu. - NIL

Start Date03 Jul 2024

Sponsor / Collaborator-

TCTR20240606006

/ Not yet recruitingPhase 1IIT

The Effectiveness of Traditional Acehnese Coconut Oil as a Moisturizer in Patients with Xerosis Cutis at Dr. Zainoel Abidin Regional General Hospital

Start Date01 Jul 2024

Sponsor / Collaborator-

100 Clinical Results associated with Asteatosis cutis

100 Translational Medicine associated with Asteatosis cutis

0 Patents (Medical) associated with Asteatosis cutis

339

Literatures (Medical) associated with Asteatosis cutis

22 Apr 2025·International journal of dermatology

Basic Emollients for the Management of Xerosis Cutis: Biophysical Properties, Clinical Evidence, and Practical Considerations.

Author: Wollenberg, Andreas

15 Apr 2025·International journal of dermatology

Restoring Skin Hydration and Barrier Function: Mechanistic Insights Into Basic Emollients for Xerosis Cutis.

Article

Author: Fluhr, Joachim W ; Christen-Zaech, Stéphanie ; Muguet, Valérie

Healthy skin is structured to maintain water balance by maximizing water retention and minimizing evaporative loss. The water-holding and barrier functions of the skin can be impaired by several factors that lead to xerosis cutis (dry skin); however, they can also be restored by basic emollients that act through the physicochemical properties of their constituents. This article aims to give a narrative review of the physiology of normal skin hydration, the key pathophysiological mechanisms implicated in dry skin, and the functional effects of basic emollients for managing xerosis cutis. Skin hydration is primarily mediated by the stratum corneum (SC), the outermost layer of the epidermis. Hygroscopic compounds in the SC maintain the skin's water-binding capacity, while the intercellular lipid bilayer and outer hydrolipid film prevent evaporative water loss. Xerosis cutis is characterized by a reduction in natural moisturizing factors or hydrolipids in the SC; it may be caused by exogenous triggers (e.g., cold weather, lifestyle, pollution), endogenous factors (e.g., aging, medication use) or genetic predisposition (as seen in atopic dermatitis, psoriasis, ichthyosis), or it may present as a symptom of a systemic disease (e.g., diabetes mellitus, hypothyroidism). Regardless of the underlying cause, basic emollients are recommended for the treatment of xerosis cutis and are typically formulated with humectants to improve skin hydration and water-holding capacity (e.g., glycerol, urea, lactic acid) and occludents to restore the epidermal barrier (e.g., petrolatum, liquid paraffin). Basic emollients remain the standard of care for the long-term management of xerosis cutis and diseases associated with dry skin.

01 Mar 2025·Clinics in Dermatology

Xerosis cutis and wounded skin in modern art: Two works by Alberto Burri

Article

Author: Hoenig, Leonhard J ; Parish, Lawrence Charles ; Wollina, Uwe

The human skin has been a subject of medicine and art. The interest in the interaction of skin and the inner body had increased after the establishment of anatomy as a science long before dermatology was acknowledged as a medical discipline. In painting the body surface, the Inkarnat (flesh tone) represents a mixture of the superficial epidermis and dermis, plus the deeper musculature and vasculature, each contributing to the skin color. In the fine arts of the Renaissance, skin is understood as primarily a layer of material. The human skin can express feelings, emotions, and various states of mind. We analyze two works of the Italian artist Alberto Burri (1915-1995), who painted in the postwar period. He opens a window into human existence with his materials while showing tragedies and wounds.

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Asteatosis cutis

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