Synonyms GIGANTISM, GIGANTISM, PITUITARY, Genetic giant + [32] |
Introduction The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age. |
Target |
Mechanism SSTR antagonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. CN |
First Approval Date14 Mar 2002 |
Target |
Mechanism DRDs agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date28 Jun 1978 |
Start Date01 Jan 2024 |
Sponsor / Collaborator- |
Start Date01 Apr 2023 |
Sponsor / Collaborator |
Start Date03 Oct 2022 |
Sponsor / Collaborator- |