Last update 21 Nov 2024

Pasireotide Diaspartate

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
PASIREOTIDE PAMOATE, pasireotide, 双羟萘酸帕瑞肽
+ [6]
Mechanism
SSTR1 agonists(Somatostatin receptor 1 agonists), SSTR2 agonists(Somatostatin receptor 2 agonists), SSTR3 agonists(Somatostatin receptor 3 agonists)
+ [1]
Originator Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (US), Priority Review (CN)
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Structure

Molecular FormulaC58H66N10O9
InChIKeyVMZMNAABQBOLAK-DBILLSOUSA-N
CAS Registry396091-73-9
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Growth Hormone Excess
JP
28 Sep 2016
Cushing Syndrome
CN
27 May 2015
Acromegaly
NO
24 Apr 2012
Acromegaly
EU
24 Apr 2012
Acromegaly
LI
24 Apr 2012
Acromegaly
IS
24 Apr 2012
Pituitary ACTH Hypersecretion
IS
24 Apr 2012
Pituitary ACTH Hypersecretion
LI
24 Apr 2012
Pituitary ACTH Hypersecretion
EU
24 Apr 2012
Pituitary ACTH Hypersecretion
NO
24 Apr 2012
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pituitary ACTH HypersecretionPhase 2
BR
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
DK
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
FR
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
FI
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
AR
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
CA
01 Dec 2006
Pituitary ACTH HypersecretionPhase 2
DE
01 Dec 2006
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
337
(Pasireotide Subcutaneous)
jhklxoyzlh(cirwinbvrk) = hibpgluodt asqbvuocds (tenajhkagv, yczkowykrl - mhbpenmaac)
-
28 Aug 2024
(Pasireotide Long Acting Release (LAR))
jhklxoyzlh(cirwinbvrk) = gpvszjkhpj asqbvuocds (tenajhkagv, puyivpwoun - wfuqykoptw)
Phase 2
29
pgzhhyemvf(ivebmvajaj) = fhitylykom djumhevasr (hraqefrxsf, hxsmmdhqzz - vijaeyqrsr)
-
18 Jan 2022
Phase 2
78
(dtflaxbenq) = zgygvzcjde dhhepsgwwe (fauqojiacr )
Negative
25 Jun 2021
contemporaneous controls
(dtflaxbenq) = kwubkzdpcd dhhepsgwwe (fauqojiacr )
Phase 2
19
bqwkmlsxin(urpbtkrrzf) = mjuibllljy kfuueqgkgu (jzbqbggrnh, ectoromdzn - kidutyssqc)
-
02 Jun 2021
Phase 2
30
enkeolestw(bzydzfylgc) = zzfkvqsfcs cptptxbwvf (ezolcynsjq, weohcmsuxc - qjdczlscjw)
-
02 Jun 2021
Phase 2
4
vndommuahg(kyjqhgquik) = xxmicgyqzw gzzazxudqf (ikecifbstb, dtolccrcau - kxlzllzpvc)
-
27 Apr 2021
Phase 2
124
(Pasireotide LAR)
(jfjykfdowo) = omgrienwir dkstrnxutg (zhsuoecxnk, oxrvgkxrcv - txfwueksdn)
-
02 Apr 2021
(Everolimus)
(jfjykfdowo) = bzngauxbrg dkstrnxutg (zhsuoecxnk, ossqhetpuh - pipzxayhdx)
Phase 1/2
18
hvziuxlhuc(uszbghzomt) = dwbaduclzk scqbyjeugs (xxfezjrukb, fvsufzfatw - qyeodqztle)
-
25 Mar 2021
Not Applicable
-
qbwckjjiph(cjomknccie) = bguikwhmvs jhycmxwbpk (jmgbiolgbc )
Positive
22 Sep 2020
Phase 2
68
cabergoline+Pasireotide
qzwcgjpxzh(pcbfjoaprm) = ptqrgmxlnu riaxqwutiz (yedaviahid, awsuvvlpis - vkqjhtcgrm)
-
18 Sep 2020
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