Synonyms Complex, Disinhibition-Dementia-Parkinsonism-Amyotrophy, Complex, Disinhibition-Dementia-Parkinsonism-Amytrophy, Complices, Disinhibition-Dementia-Parkinsonism-Amyotrophy + [97] |
Introduction The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with personality and behavioral changes often associated with disinhibition, apathy, and lack of insight. |
Target |
Mechanism TAU modulators |
Active Org. |
Originator Org. |
Active Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date28 May 2020 |
Target |
Mechanism APP modulators [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. US |
First Approval Date06 Apr 2012 |
Target |
Mechanism COX inhibitors |
Active Org. NeuroTau, Inc.Startup [+1] |
Originator Org. |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. CN |
First Approval Date13 Jul 2005 |
Start Date01 Jun 2024 |
Sponsor / Collaborator |
Start Date06 May 2024 |
Sponsor / Collaborator |
Start Date01 May 2024 |
Sponsor / Collaborator |