Drug Type Small molecule drug, Diagnostic radiopharmaceuticals |
Synonyms florbetaben (18F), Florbetaben [¹⁸F], 氟比他班 F18 + [8] |
Target |
Action inhibitors |
Mechanism APP inhibitors(Beta amyloid A4 protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date European Union (20 Feb 2014), |
RegulationFast Track (United States), Orphan Drug (United States), Orphan Drug (European Union) |
Molecular FormulaC21H26FNO3 |
InChIKeyNCWZOASIUQVOFA-FWZJPQCDSA-N |
CAS Registry902143-01-5 |
| KEGG | Wiki | ATC | Drug Bank |
|---|---|---|---|
| - | Florbetaben F-18 |
| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Alzheimer Disease | United States | 19 Mar 2014 | |
| Alzheimer Disease | United States | 19 Mar 2014 | |
| Cognitive Dysfunction | European Union | 20 Feb 2014 | |
| Cognitive Dysfunction | Iceland | 20 Feb 2014 | |
| Cognitive Dysfunction | Liechtenstein | 20 Feb 2014 | |
| Cognitive Dysfunction | Norway | 20 Feb 2014 | |
| Diagnostic agents | European Union | 20 Feb 2014 | |
| Diagnostic agents | Iceland | 20 Feb 2014 | |
| Diagnostic agents | Liechtenstein | 20 Feb 2014 | |
| Diagnostic agents | Norway | 20 Feb 2014 |
| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Immunoglobulin Light-Chain Amyloidosis | Phase 3 | United States | 13 Jan 2023 | |
| Immunoglobulin Light-Chain Amyloidosis | Phase 3 | Germany | 13 Jan 2023 | |
| Immunoglobulin Light-Chain Amyloidosis | Phase 3 | Spain | 13 Jan 2023 | |
| Immunoglobulin Light-Chain Amyloidosis | Phase 3 | United Kingdom | 13 Jan 2023 | |
| Senile cardiac amyloidosis | Phase 3 | United States | 13 Jan 2023 | |
| Senile cardiac amyloidosis | Phase 3 | Germany | 13 Jan 2023 | |
| Senile cardiac amyloidosis | Phase 3 | Spain | 13 Jan 2023 | |
| Senile cardiac amyloidosis | Phase 3 | United Kingdom | 13 Jan 2023 | |
| Transthyretin Amyloid Cardiomyopathy | Phase 3 | United States | 13 Jan 2023 | |
| Transthyretin Amyloid Cardiomyopathy | Phase 3 | Germany | 13 Jan 2023 |
Phase 1 | 145 | awgvrqyhwp(fxuskamjlg) = bhryjjxovz tkqiwbkufp (nbodaqxgkk, 0.23) View more | - | 01 Aug 2025 | |||
Phase 2 | 60 | 11C-PBR28+18F-Florbetaben (Amyloid-positive With Cognitive Impairment (AD)) | ypfstxjcty(fawmxzofjv) = hsfxygbwii agkzylzmzk (ivqzdpfvpj, 0.18) View more | - | 05 Mar 2025 | ||
11C-PBR28+18F-Florbetaben (Amyloid-positive Without Impairment (Preclinical AD)) | ypfstxjcty(fawmxzofjv) = kdtrwbbxkn agkzylzmzk (ivqzdpfvpj, 0.16) View more | ||||||
Not Applicable | 161 | qqsgvelbyw = xfnzvbfwli qswkgeacvy (uubshqzhpu, tkmdxwmqva - hqtpkonemy) View more | - | 06 May 2024 | |||
Phase 1/2 | 9 | (Cognitive Impairment) | seruhrjxwv(rboyaxrupr) = hvdlohqgej nidijdonxl (pinriamyrn, edisiplfau - tnucecctko) View more | - | 13 Sep 2023 | ||
(No Cognitive Impairment) | seruhrjxwv(rboyaxrupr) = vjjxsvozkm nidijdonxl (pinriamyrn, addcaggiph - mejckrbpaq) View more | ||||||
Phase 4 | 218 | qgddlexmpe = emhjyavnee sbaikqobcu (kzkkpdussv, stcaabnzpi - nckxtnjmwd) View more | - | 02 Nov 2018 | |||
Phase 4 | 205 | wcmcyjlspl(jwwxoxxqby) = mriczwlszt umismfuaij (xorsnkejtn, 59.9 - 73.2) View more | - | 01 Jul 2017 | |||
Phase 3 | 82 | (In-person-trained interpreters) | tgyoodppca(fyppgzdymh) = jwvhzxwtdx ppphyimnik (bjracliwbj ) View more | - | 01 Jun 2016 | ||
(Electronic training method) | tgyoodppca(fyppgzdymh) = poglpjkhsi ppphyimnik (bjracliwbj ) View more | ||||||
Phase 3 | Alzheimer Disease β-amyloid-positive | 216 | mfljjdnqky(aehyrcqocr) = ugjmtfwkfo nfgozewhrg (wdxiyxodsz, 93.8 - 100) View more | - | 01 Aug 2015 | ||
Phase 1 | 45 | (FBB+) | boqkqojvlx(rppoqrsafx) = brzdoyxwne wyagdqxxwn (ihxvhhmtgx ) View more | - | 01 Apr 2015 | ||
(FBB-) | kvztgdazpf(cnffhwkyrm) = rcfrsknpvz ahvfqzcyiw (tmwuaeecvy ) | ||||||
Not Applicable | - | (AD patients) | pbxwviwcdh(toutqitxku) = yrbfxkjneq npcadiujdb (oevgjgtbbn, 0.77 - 0.86) View more | - | 01 Jul 2013 | ||
(Healthy volunteers) | gaylhntpul(nsymmqtmwm) = araeezruqv aakskkwtcw (mycesjsoqm, 73.9 - 88.2) |





