Synonyms CARDIOPULMONARY OBESITY SYNDROME, Extreme obesity with alveolar hypoventilation, Extreme obesity with alveolar hypoventilation (disorder) + [29] |
Introduction HYPOVENTILATION syndrome in very obese persons with excessive ADIPOSE TISSUE around the ABDOMEN and DIAPHRAGM. It is characterized by diminished to absent ventilatory chemoresponsiveness; chronic HYPOXIA; HYPERCAPNIA; POLYCYTHEMIA; and long periods of sleep during day and night (HYPERSOMNOLENCE). It is a condition often related to OBSTRUCTIVE SLEEP APNEA but can occur separately. |
Target |
Mechanism CAs inhibitors [+1] |
Active Org. Apnimed, Inc.Startup [+1] |
Originator Org.- |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date01 May 2024 |
Sponsor / Collaborator |
Start Date10 Apr 2024 |
Sponsor / Collaborator Istanbul University [+1] |
Start Date10 Apr 2024 |
Sponsor / Collaborator Istanbul University [+1] |