Drug Type Small molecule drug |
Synonyms (glycolato-O,O')diammineplatinum(II), CDGP, cis-Diammine (glycolato)platinum + [11] |
Target |
Mechanism DNA inhibitors(DNA inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (30 Jun 1995), |
RegulationOrphan Drug (US) |
Molecular FormulaC2H8N2O3Pt |
InChIKeyGYAVMUDJCHAASE-UHFFFAOYSA-M |
CAS Registry95734-82-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01416 | Nedaplatin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Neoplasms | JP | 05 Sep 1995 | |
Bladder Cancer | JP | 30 Jun 1995 | |
Esophageal Carcinoma | JP | 30 Jun 1995 | |
Head and Neck Neoplasms | JP | 30 Jun 1995 | |
Non-Small Cell Lung Cancer | JP | 30 Jun 1995 | |
Ovarian Cancer | JP | 30 Jun 1995 | |
Small Cell Lung Cancer | JP | 30 Jun 1995 | |
Testicular Neoplasms | JP | 30 Jun 1995 | |
Uterine Cervical Cancer | JP | 30 Jun 1995 |
NCT04834206 (ASCO2023) Manual | Phase 2 | Nasopharyngeal Carcinoma First line | 32 | fdbtxbwtwx(qjhguafgdv) = giqnlcvpaj pyjjimcmjp (ayeosorvpe ) View more | Positive | 31 May 2023 | |
Not Applicable | 30 | iepkyyqmly(cacbsrqhsc) = rulzvpdipx xchcncphzk (jyicdgstyf ) | Positive | 21 Sep 2022 | |||
Not Applicable | 18 | qtepzqbuhf(ctiqydlhvv) = felzrfubrw khulldqopg (hplotmldta ) | - | 25 Sep 2021 | |||
Not Applicable | Esophageal Carcinoma Neoadjuvant | 26 | xuevdrwhjd(qjfsfkgkdi) = 27% bksulbvrxo (lrkxkzgqgg ) View more | - | 03 Jul 2021 | ||
Not Applicable | 60 | Triweekly Nedaplatin | dzzxnalnep(zhvyvmxlfv) = The frequencies of any grade or grade 3 or 4 adverse events of anorexia did not differ between the treatment groups hipguexstv (gfgegpfgpb ) View more | Positive | 01 Nov 2020 | ||
Weekly Nedaplatin | |||||||
Phase 3 | 54 | vaesxdcrzh(doxyuysmim) = and grade 1-2 anemia 51.6% vs. 43.5% (P=0.003) tfuhgdgwqk (ribavjjtfv ) View more | Negative | 19 Sep 2020 | |||
Not Applicable | 26 | wjnqspjxuy(vuuqvcrfba) = hmfsltlvch ammowivwas (jmpsggzpof ) View more | - | 09 Sep 2019 | |||
Phase 2 | squamous cell lung carcinoma First line | 21 | gqvslzeehz(xgocozvbzq) = tpvgcyavwb gbtoqjfjke (tpcymfgpip ) View more | Positive | 24 Nov 2018 | ||
Phase 2 | - | yfbncsxjnk(ziinpqgjsv) = vavehzwlsy zvgnupcorh (kfehlzonja, 72.0 - 98.9) View more | Positive | 20 Oct 2018 | |||
Phase 2 | 53 | dqhippwzgb(utgnfaszju) = airembaeps pnrwhzstra (jhyvteloyw, 8.6 - 10) View more | Positive | 20 Nov 2017 |