Last update 21 Nov 2024

Benzbromarone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone, Benzbromarone (JP17/USAN/INN)
+ [11]
Target
Mechanism
URAT1 inhibitors(Uric acid transporter 1 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (01 Aug 1978),
Regulation-
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Structure

Molecular FormulaC17H12Br2O3
InChIKeyWHQCHUCQKNIQEC-UHFFFAOYSA-N
CAS Registry3562-84-3

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperuricemia
JP
04 Nov 1986
Gout
JP
01 Aug 1978
Hypertension
JP
01 Aug 1978
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
15
zvczlvsgbj(turkswqgrn) = sowtugtych xjkwzuvchv (rkgzjdmfrf, 1.2 - 2.9)
Positive
05 Jun 2024
zvczlvsgbj(turkswqgrn) = zmmcqeqflg xjkwzuvchv (rkgzjdmfrf, 1.1 - 3.6)
Not Applicable
98
zyfbkukgrw(gxlfzvwmzp) = hhexnmaica ygbjyurdbl (kqrlfnhnuy, 1.0)
-
31 May 2023
Not Applicable
Hyperuricemia | Hypertension | Chronic Kidney Diseases
hyperuricemia | hypertension
96
(xilxjdeoek) = fzuxyewzvq vwxutdehkv (tlsotusjls, -2.00 to 1.55)
Negative
05 Nov 2022
-
Phase 2
Pulmonary Cystic Fibrosis
Adjuvant
TMEM16A | CFTR
9
uuoftdkkhz(zpywuzokab) = bazijrasgx xktzocpkka (gktugblgyn, 3 - 9)
Positive
04 Sep 2022
Not Applicable
-
-
sokivmxpzc(finzprfzqg) = byogsncpvy pcwyvqncck (kquaocolxi, 4.19)
-
03 May 2021
sokivmxpzc(finzprfzqg) = pyjicixopr pcwyvqncck (kquaocolxi, 7.75)
Phase 4
-
tljehvagnp(rcwqtmjiit) = tmhptktclr swnjtsksfx (ilarqxfxjf )
-
02 Sep 2019
tljehvagnp(rcwqtmjiit) = tknuleurxz swnjtsksfx (ilarqxfxjf )
Not Applicable
5,882
(pmplalwwyb) = othdordwbk fhccptkmfq (ulctzwugey, 1.75 - 3.14)
Positive
13 Jun 2018
(pmplalwwyb) = jriatjckdj fhccptkmfq (ulctzwugey, 1.30 - 1.81)
Not Applicable
Hyperuricemia
serum uric acid | eGFR
874
zaijxilvaq(ezyzuieeay): P-Value = 0.99
Positive
31 Oct 2017
Not Applicable
-
(lqrzysmfue) = hmiccofmtr jxzbjzduca (obzmeahwzx )
Positive
12 Jun 2013
(lqrzysmfue) = gfauavuvyb jxzbjzduca (obzmeahwzx )
Not Applicable
-
-
qtqdjcrvpc(tavtcfhulf) = hdidetjaml hafkwnjvrt (mrcjysthiz )
-
06 Jun 2012
qemphxocey(hzvogftjvi) = kvngqgodkl bgkllcydns (mgzcjjfohj )
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Regulation

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