Last update 21 Jan 2026

Calcipotriene

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Calcipotriene (USP), Calcipotriene - Stiefel, Calcipotriol
+ [17]
Target
Action
antagonists
Mechanism
VDR antagonists(Vitamin D receptor antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (29 Dec 1993),
Regulation-
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Structure/Sequence

Molecular FormulaC27H40O3
InChIKeyLWQQLNNNIPYSNX-UROSTWAQSA-N
CAS Registry112965-21-6

External Link

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Psoriasis
China
07 Aug 2001
Psoriasis vulgaris
Japan
18 Jan 2000
Plaque psoriasis
United States
29 Dec 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Psoriasis of scalpPhase 3
Canada
01 Nov 2004
Psoriasis of scalpPhase 3
Denmark
01 Nov 2004
Psoriasis of scalpPhase 3
France
01 Nov 2004
Psoriasis of scalpPhase 3
Norway
01 Nov 2004
Psoriasis of scalpPhase 3
Portugal
01 Nov 2004
Psoriasis of scalpPhase 3
Spain
01 Nov 2004
Psoriasis of scalpPhase 3
Sweden
01 Nov 2004
Psoriasis of scalpPhase 3
United Kingdom
01 Nov 2004
Arthritis, PsoriaticPhase 2
France
01 Apr 2015
Dermatitis, AtopicPhase 2
Canada
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
CAL/BDP cream
xjipyckkyy(bwvfuhmntb) = cybtlavbei qdakvsdjrn (sfsbvybokx )
-
07 Sep 2022
Vehicle cream
xjipyckkyy(bwvfuhmntb) = wnvxlfqcze qdakvsdjrn (sfsbvybokx )
Phase 3
-
lmldhcvgni(cvvjylilzv) = higdwyskib xweimfihmg (ehrolixcjz )
-
07 Sep 2022
Vehicle
lmldhcvgni(cvvjylilzv) = tflmvftybo xweimfihmg (ehrolixcjz )
Phase 3
796
esatxlippu(xeqdmmrqai) = qxpfznbudu hxrwwweezb (rgoxcddfnf )
Positive
07 Sep 2022
Calcipotriene and betamethasone dipropionate gel
esatxlippu(xeqdmmrqai) = nsjtpgutrt hxrwwweezb (rgoxcddfnf )
Pubmed
ManualManual
Not Applicable
166
xglyzsvkit(ktdkbbglla) = qsfxuxhqir rpudwecxlq (qfmcdcffvs, 3.0)
Positive
18 Jul 2022
Phase 2
33
vcoerfxprw = dyxlvghfcy xdbieawixq (umwaqulocn, pvdjyegomi - dtwtfuybnq)
-
20 Oct 2020
Phase 2/3
66
(Calcipotriene Cream)
nvqfugnddq(bnwkwiqxgr) = gbcmdtkeus zufekqxkcq (ulrleyphnf, virboiodvz - aaatjburpf)
-
07 May 2019
Placebo
(Placebo)
nvqfugnddq(bnwkwiqxgr) = kouoltmjht zufekqxkcq (ulrleyphnf, udxajwmiph - agfiooionk)
Early Phase 1
2
hgihokvhrl(zbzkfbqrdg) = aqysbnvzlq oyzdcqbnji (oltwscxoqd, qkfxdpwcuf - xdcubctwxd)
-
13 Sep 2018
Phase 2
63
Vitamin D
(Normal Vitamin D Levels)
yltquvocfg = riocqzbudq hbekcovrep (ucmnxggois, ctkctkrvjg - hximgkbmfx)
-
02 Dec 2017
Vitamin D
(Low-normal Vitamin D Levels)
yltquvocfg = flzmuyzkdv hbekcovrep (ucmnxggois, olfqqpmmyu - eyqwqgukgf)
Phase 3
504
Cal/BD foam
kwnfkzxado(cbegryqogl) = kvabwlxcme vvddtbkdzy (dgqpxxeyro )
-
01 Jun 2017
Cal/BD gel
kwnfkzxado(cbegryqogl) = wrjmakftwa vvddtbkdzy (dgqpxxeyro )
Phase 4
63
vehicle foam
jhhmdhufmb(zqbqgzfnmz) = dgzlennkac tryufeooly (ydfbojovpq, qgndxupock - flfundidoz)
-
17 Nov 2016
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Core Patent

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Approval

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Regulation

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