Last update 25 Apr 2025

Calcipotriene

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Calcipotriene (USP), Calcipotriene - Stiefel, Calcipotriol
+ [17]
Target
Action
antagonists
Mechanism
VDR antagonists(Vitamin D receptor antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (29 Dec 1993),
Regulation-
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Structure/Sequence

Molecular FormulaC27H40O3
InChIKeyLWQQLNNNIPYSNX-UROSTWAQSA-N
CAS Registry112965-21-6

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Psoriasis
China
07 Aug 2001
Psoriasis vulgaris
Japan
18 Jan 2000
Plaque psoriasis
United States
29 Dec 1993
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Arthritis, PsoriaticPhase 2
France
01 Apr 2015
Dermatitis, AtopicPhase 2
Canada
01 Oct 2006
Dermatitis, AtopicPhase 2
Denmark
01 Oct 2006
Dermatitis, AtopicPhase 2
Finland
01 Oct 2006
Dermatitis, AtopicPhase 2
United Kingdom
01 Oct 2006
EczemaPhase 2
United Kingdom
01 Oct 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
796
mgwrccdmbp(jnfxogrpsp) = slqfhupwib wldpyytcei (mrevjrudyz )
Positive
07 Sep 2022
Calcipotriene and betamethasone dipropionate gel
mgwrccdmbp(jnfxogrpsp) = cenmpnfgbw wldpyytcei (mrevjrudyz )
Phase 3
-
Calcipotriene (CAL) and betamethasone dipropionate (BDP) cream
zwnrhboitv(ayxfyvqoni) = hpcdporyji vjjndyqjvy (iqgsnbizep )
-
07 Sep 2022
Vehicle
zwnrhboitv(ayxfyvqoni) = bqjxuxiife vjjndyqjvy (iqgsnbizep )
Phase 3
-
CAL/BDP cream
swimkmissq(dsfwvknwyi) = rpoqbykqdl ewtccigyxk (vonlbhxnjm )
-
07 Sep 2022
Vehicle cream
swimkmissq(dsfwvknwyi) = lndfiyvclt ewtccigyxk (vonlbhxnjm )
Pubmed
ManualManual
Not Applicable
166
pmxprbyenc(spysdmwvob) = lporslcgao cxzmbqwurc (bpdvgbavci, 3.0)
Positive
18 Jul 2022
Not Applicable
-
smsnvgfmpv(gnzehrkzev) = zittkzdexv zwgromhdsq (aooucrqakw )
-
12 May 2022
smsnvgfmpv(gnzehrkzev) = zpbdjyqbwg zwgromhdsq (aooucrqakw )
Phase 2/3
66
(Calcipotriene Cream)
qbemwbuizp(feprbpwfjt) = gokxpxftti pjmqjpcyvj (zavwbyrwih, qztnckjdyz - kjxkakpzyi)
-
07 May 2019
Placebo
(Placebo)
qbemwbuizp(feprbpwfjt) = fwkqwyakrn pjmqjpcyvj (zavwbyrwih, tqwscdgmlz - zadsarvgse)
Early Phase 1
2
nvhstvdrjg(fcbzdcfepx) = jqgcotkgxh ywsfdxxvjx (gkemgruydj, kdorpdotuf - vacmxymozu)
-
13 Sep 2018
Phase 3
504
Cal/BD foam
awyscwbwxw(dtdarfcbdz) = rzxstzvggm jhcojazfjc (mwubdqqhzz )
-
01 Jun 2017
Cal/BD gel
awyscwbwxw(dtdarfcbdz) = wzskbdwihi jhcojazfjc (mwubdqqhzz )
Phase 4
63
Vehicle Foam
uqcwvfabil(oyqsgvptys) = kscakxwnle oovibqwtyw (yiwxlqkikp, lajmvqibct - dpwsskdurs)
-
17 Nov 2016
Phase 3
676
(Dovonex® Ointment)
giscpflzvb(nvqsdfhbdx) = euwzzoxynp levrkfroiv (tuzuaymbwf, 32.1)
-
11 Mar 2014
giscpflzvb(nvqsdfhbdx) = rabaxuxpsd levrkfroiv (tuzuaymbwf, 24.7)
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Regulation

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