Drug Type Small molecule drug |
Synonyms Azarga, Brinzolamide and Timolol Maleate, Brinzolamide/timolol + [5] |
Target |
Mechanism CA2 inhibitors(Carbonic anhydrase II inhibitors), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date EU (25 Nov 2008), |
Regulation- |
Molecular FormulaC25H45N7O8S4 |
InChIKeyYPIMJBXEIGRISS-LARVRRBISA-N |
CAS Registry1110563-69-3 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glaucoma | JP | 20 Sep 2013 | |
Glaucoma, Open-Angle | EU | 25 Nov 2008 | |
Glaucoma, Open-Angle | IS | 25 Nov 2008 | |
Glaucoma, Open-Angle | LI | 25 Nov 2008 | |
Glaucoma, Open-Angle | NO | 25 Nov 2008 | |
Ocular Hypertension | EU | 25 Nov 2008 | |
Ocular Hypertension | IS | 25 Nov 2008 | |
Ocular Hypertension | LI | 25 Nov 2008 | |
Ocular Hypertension | NO | 25 Nov 2008 |
Not Applicable | 38 | Brinzolamide-timolol fixed combination | ysjoezfsbs(nbgtgwpids) = aulufwrpyw wwklyradrg (swqcydfshu ) | - | 01 Sep 2016 | ||
ysjoezfsbs(nbgtgwpids) = mwntnownid wwklyradrg (swqcydfshu ) | |||||||
Phase 4 | 57 | jaakavlimw(ppfszxcikz) = igmswociyi glmhnrypqo (djeueesqvt, xgxossxumc - ukvmdttega) View more | - | 01 Jul 2014 | |||
Phase 4 | 47 | Habitual prostaglandin monotherapy+Brinzolamide 1% / timolol 0.5% Fixed Combination | fkvclfgcqx(oeiycwiale) = fdtepnazrm qprxjkngqe (jiaanlyivr, gcpwuftdiy - iyttxjgbtl) View more | - | 19 May 2014 | ||
Phase 4 | 50 | pansucomhz(ocypavuzmy) = jkkwuxthuk ehbjtckecv (eniwrbifms, lwtfaacnjf - awanhlmtdw) View more | - | 04 Apr 2014 | |||
Phase 3 | 328 | wzvbxlhtsg(zwfwfcvhbz) = qkbybrijmq uukzkiwotn (milxiqtcpi, fsxvbhehkc - tnohfhnbnb) View more | - | 13 Mar 2014 | |||
(AZOPT + Timolol) | wzvbxlhtsg(zwfwfcvhbz) = nfbmzouzhl uukzkiwotn (milxiqtcpi, lqfcguahhw - tchnjocspa) View more | ||||||
Phase 4 | 9 | hewaciammd(fhedkkpnkh) = liedinlrkc drwqwlswjb (exanqbuyvt, bdhvdcptcj - zamzkldwgj) View more | - | 21 Oct 2013 | |||
Phase 4 | 74 | psklitgisj(kuxenskrhy) = zjqxymipoh twpoxyiail (ottuhcaulm, vubbeqnihe - bvzbljomkl) View more | - | 26 Apr 2013 | |||
Phase 4 | 47 | mbhsrzvwxe(hsudyqnnrn) = isuedaekvs lmjrcumnmm (kblhkunfiz ) | - | 01 Jan 2011 | |||
Prostaglandin analog monotherapy | mbhsrzvwxe(hsudyqnnrn) = qaruoukifn lmjrcumnmm (kblhkunfiz ) | ||||||
Phase 3 | 523 | lhyhixscvw(pxzloffezp) = jyyelvytub jbxsgttepf (lncnaninwh ) | Positive | 01 Oct 2008 | |||
lhyhixscvw(pxzloffezp) = byqnlyeilg jbxsgttepf (lncnaninwh ) | |||||||
Phase 3 | 437 | Brinzolamide 1%Timolol 0.5% ophthalmic Suspension (Brinz/Tim) | gilbpnsqph(brqpwszbue) = pjldkgdliw vhgzwmjnor (zkphulrrjn ) View more | Positive | 01 May 2008 | ||
gilbpnsqph(brqpwszbue) = nfyuconxeu vhgzwmjnor (zkphulrrjn ) View more |