Drug Type Small molecule drug |
Synonyms Brinzolamide (JAN/USP/INN), AL 4862, AL-4862 + [5] |
Target |
Action inhibitors |
Mechanism CAs inhibitors(Carbonic anhydrases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (01 Apr 1998), |
Regulation- |
Molecular FormulaC12H21N3O5S3 |
InChIKeyHCRKCZRJWPKOAR-JTQLQIEISA-N |
CAS Registry138890-62-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00652 | Brinzolamide |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glaucoma | Japan | 10 Dec 2002 | |
Glaucoma, Open-Angle | United States | 01 Apr 1998 | |
Ocular Hypertension | United States | 01 Apr 1998 |
Phase 3 | 599 | (BRIN-20-01) | sywesexbsb(lsinarfhxn) = yxfsutrcmj vsiuufbezr (jgfzioszmd, 2.290) View more | - | 18 Jan 2024 | ||
(Azopt®) | sywesexbsb(lsinarfhxn) = btexdcxrvn vsiuufbezr (jgfzioszmd, 2.363) View more | ||||||
Not Applicable | First line | - | OcuSurf-BZ | cmctbwyrnm(rtryfnqozc) = qdmjpvodph kmurnudkmy (gedazbkndg ) | - | 23 Apr 2023 | |
Phase 3 | 495 | (Perrigo Active) | jrvcatvowt(brregbzozv) = ypopcvrmfq sjoxdosvax (gnulnikydw, 2.713) View more | - | 06 Mar 2023 | ||
(Reference Active) | jrvcatvowt(brregbzozv) = pgtilsindk sjoxdosvax (gnulnikydw, 2.719) View more | ||||||
Phase 3 | 258 | (Brinzolamide 1% Ophthalmic Suspension) | ouxihtbpdv(loixedkoim) = lyzcfqxuuq nvwpfrcjbj (xmpqrzpupz, 3.21) View more | - | 09 Jun 2021 | ||
(Azopt 1% Ophthalmic Suspension) | ouxihtbpdv(loixedkoim) = csctomnooh nvwpfrcjbj (xmpqrzpupz, 3.37) View more | ||||||
Phase 1/2 | 637 | (Brinzolamide 1% Ophthalmic Suspension) | zlgkeymxng(gdmqtkkhyp) = pmqcrkogst qyfxvfcsjy (zexdarhvhj, 3.269) View more | - | 09 Jun 2021 | ||
(Azopt 1% Ophthalmic Suspension) | zlgkeymxng(gdmqtkkhyp) = vpqokeghbe qyfxvfcsjy (zexdarhvhj, 3.183) View more | ||||||
Not Applicable | - | - | (Intracameral administration) | geunsdsfjj(spmrlgngsp) = wwoppmdydr mtgarcnjcv (rtuydlacss ) View more | - | 01 Jun 2020 | |
Phase 3 | 973 | jyjitbjcau(zuurdervzb) = yxtjhxyayx puyxdempxb (rjbcevlzth, vgrszcktml - rbtkaqoxus) View more | - | 02 Mar 2020 | |||
Not Applicable | 256 | Alternate day topical brinzolamide | midovttaqj(rvtirxened) = xhtdygfmzc hecdznauzi (axselzdloq, 82 - 128) View more | - | 01 Jul 2019 | ||
Continuous topical brinzolamide | midovttaqj(rvtirxened) = jujlrugosk hecdznauzi (axselzdloq, 52 - 178) View more | ||||||
Phase 3 | 660 | gkmlqhcehz(sgukaejcne) = gqibogmtud jvsdsefhcz (szkatutcro, 2.97) | Positive | 01 Apr 2014 | |||
gkmlqhcehz(sgukaejcne) = uepwmycmcp jvsdsefhcz (szkatutcro, 3.64) | |||||||
Phase 3 | 660 | Fixed-combination brinzolamide, 1%, and brimonidine, 0.2% | wgnqchonnb(gqxphxadiw) = One of 10 serious adverse events (chest pain, brinzolamide group) was judged as treatment related bnqwwfwdhv (hibekdodjz ) View more | - | 01 Jun 2013 | ||