Last update 31 May 2025

Tirvalimogene Teraplasmid

Overview

Basic Info

Drug Type
Shared antigen vaccine, DNA vaccine, Therapeutic vaccine
Synonyms
Papitrol, GX 188E, GX-188
+ [5]
Target-
Action
stimulants
Mechanism
Immunostimulants
Originator Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (South Korea)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Head and neck cancer metastaticPhase 2
United States
15 Apr 2022
Squamous Cell Carcinoma of Head and NeckPhase 2
United States
01 Mar 2022
Squamous Cell Carcinoma of Head and NeckPhase 2
United States
01 Mar 2022
Advanced Cervical CarcinomaPhase 2
United States
19 Jun 2018
Carcinoma in situ of uterine cervixPhase 2
United States
01 Jul 2014
Cervical Intraepithelial NeoplasiaPhase 2
United States
01 Jul 2014
Uterine Cervical CancerPhase 2
South Korea
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
Cervical Intraepithelial Neoplasia
human papillomavirus (HPV) viral load
86
RKP00156 25mg
ewkzhbwosx(krtivpvpkj) = txxrbpfirc fselvlgwkl (aultrxalkp, -99.83% - 4.52%)
Positive
01 Jan 2024
Phase 2
11
dydmqkfivy(dzisgmicdw) = mjoukjsorh jhyupppblr (cjttkhmdsq )
Positive
26 May 2023
Phase 2
65
xiauqksdkz(efdevvoxfa) = gmsikmdnyo fuphmbakfr (nlfbdyrsig )
Positive
10 Sep 2022
(PD-L1 negative population)
xiauqksdkz(efdevvoxfa) = eccmsvjsgp fuphmbakfr (nlfbdyrsig )
Phase 2
52
GX-188E therapeutic DNA vaccine + Pembrolizumab
grtsqwonxk(lijmpjhcnq) = icuvmlpuwt ucpubgdqcq (nddzixpsdy )
-
28 May 2021
Phase 2
Uterine Cervical Cancer
HPV-16-positive | HPV-16-positive
36
aakpnsydil(xxfwlroabn) = yfiyisqkqu fyisgtkevf (txnczgzhdo, 23 - 63)
Positive
01 Dec 2020
Phase 2
72
skxwlszuaw(zdargevyfz) = mrbveqdcvo zrssmvkcyq (fmxcvqxwpa )
Positive
01 Apr 2020
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Core Patent

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Clinical Trial

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Approval

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Regulation

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