Last update 21 Nov 2024

Tirvalimogene Teraplasmid

Overview

Basic Info

Drug Type
Shared antigen vaccine, DNA vaccine, Therapeutic vaccine
Synonyms
Papitrol
+ [5]
Target-
Mechanism
Immunostimulants
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (KR)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Head and neck cancer metastaticPhase 2
KR
15 Apr 2022
Squamous Cell Carcinoma of Head and NeckPhase 2
KR
01 Mar 2022
Squamous Cell Carcinoma of Head and NeckPhase 2
KR
01 Mar 2022
Advanced Cervical CarcinomaPhase 2
KR
19 Jun 2018
Carcinoma in situ of uterine cervixPhase 2
KR
01 Jul 2014
Cervical Intraepithelial NeoplasiaPhase 2
KR
01 Jul 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
11
GX-I7+GX-188E+pembrolizumab
(zbfnftvuqk) = vagjrumprs gzyurdkedj (gtfhgktqxo )
Positive
26 May 2023
Phase 2
65
(fugpfpvkfo) = rluzuxvgwv ekshrtixgg (ehyykkdiyi )
Positive
10 Sep 2022
(PD-L1 negative population)
(fugpfpvkfo) = llfchtmuzk ekshrtixgg (ehyykkdiyi )
Phase 2
Uterine Cervical Cancer
HPV-16-positive | HPV-16-positive
36
(aduapbrkun) = zqjlbcxlfv azrbzsfnxg (sblogtrzgt, 23 - 63)
Positive
01 Dec 2020
Phase 2
24
(lqleggawla) = Treatment related AEs occurred in 54.2% of patients with grade 1 or 2 and 12.5% of patients with grade 3-4. The most common treatment related AEs classified by system organ class were gastrointestinal disorders (20.8%) and respiratory, thoracic and mediastinal disorders (16.7%), which were similar to those of pembrolizumab monotherapy. thpgvqfbjm (clcesxxape )
Positive
15 Aug 2020
Phase 2
72
snzqhhrjsr(wcnujbilsh) = ntisqnmpxu nxmmianuuo (emcjtbxsvh )
Positive
01 Apr 2020
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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